Irregular sleeping patterns are "unequivocally" shown to lead to cancer in tests on mice, a study suggests.
'Sleep should be prescribed': what those late nights out could be costing you
Leading neuroscientist Matthew Walker on why sleep deprivation is increasing our risk of cancer, heart attack and Alzheimer’s – and what you can do about it
Bad sleep 'dramatically' alters body
A run of poor sleep can have a dramatic effect on the internal workings of the human body, say UK researchers.
Scientists discover how deep sleep builds muscle, burns fat, and boosts the brain
Scientists have discovered a surprising two-way relationship between sleep and growth hormone, revealing how the brain carefully balances physical recovery with wakefulness. The findings could help explain why poor sleep harms metabolism and brain health, potentially opening the door to new treatments for sleep and neurological disorders.
Things that Apparently Cause Cancer
What does this methodology measure anyway?
Why Sleep Deprivation Eases Depression
Glial activity reveals how sleep deprivation elevates mood
Extreme night owls: ‘I can’t tell anyone what time I go to bed’
What happens when your natural sleeping pattern is at odds with the rest of the world?
Opinion | Rethinking Sleep (Published 2012)
It’s not the quantity of sleep that restores and refreshes, but the quality.
Why We Sleep, and Why We Often Can’t
Does our contemporary obsession with sleep obscure what makes it special in the first place?
The brain functional connectome is robustly altered by lack of sleep
Sleep is a universal phenomenon necessary for maintaining homeostasis and function across a range of organs. Lack of sleep has severe health-related consequences affecting whole-body functioning, yet no other organ is as severely affected as the brain. The neurophysiological mechanisms underlying these deficits are poorly understood. Here, we characterize the dynamic changes in brain connectivity profiles inflicted by sleep deprivation and how they deviate from regular daily variability. To this end, we obtained functional magnetic resonance imaging data from 60 young, adult male participants, scanned in the morning and evening of the same day and again the following morning. 41 participants underwent total sleep deprivation before the third scan, whereas the remainder had another night of regular sleep. Sleep deprivation strongly altered the connectivity of several resting-state networks, including dorsal attention, default mode, and hippocampal networks. Multivariate classification based on connectivity profiles predicted deprivation state with high accuracy, corroborating the robustness of the findings on an individual level. Finally, correlation analysis suggested that morning-to-evening connectivity changes were reverted by sleep (control group)-a pattern which did not occur after deprivation. We conclude that both, a day of waking and a night of sleep deprivation dynamically alter the brain functional connectome.
Tall people at greater risk of cancer 'because they have more cells'
Report suggests link between height and cancer risk could simply be because there are more cells for something to go wrong in
This Is What Happens to Your Body on No Sleep
In short, nothing good—and just one bad night can trigger a cascade of side effects
Sleep Deficit: The Performance Killer
Reprint: R0610B Companies today glorify the executive who logs 100-hour workweeks, the road warrior who lives out of a suitcase in multiple time zones, and the negotiator who takes a red-eye to make an 8 AM meeting. But to Dr. Charles A. Czeisler, the Baldino Professor of Sleep Medicine at Harvard Medical School, this kind of corporate behavior is the antithesis of high performance. In fact, he says, it endangers employees and puts their companies at risk. In this interview, Czeisler describes four neurobiological functions that affect sleep duration and quality as well as individual performance. When these functions fall out of alignment because of sleep deprivation, people operate at a far lower level of performance than they would if they were well rested. Czeisler goes on to observe that corporations have all kinds of policies designed to protect employees—rules against smoking, sexual harassment, and so on—but they push people to the brink of self-destruction by expecting them to work too hard, too long, and with too little sleep. The negative effects on cognitive performance, Czeisler says, can be similar to those that occur after drinking too much alcohol: “We now know that 24 hours without sleep or a week of sleeping four or five hours a night induces an impairment equivalent to a blood alcohol level of .1%. We would never say, ‘This person is a great worker! He’s drunk all the time!’ yet we continue to celebrate people who sacrifice sleep for work.” Czeisler recommends that companies institute corporate sleep policies that discourage scheduled work beyond 16 consecutive hours as well as working or driving immediately after late-night or overnight flights. A sidebar to this article summarizes the latest developments in sleep research.
Depression linked to internal jet lag study finds
Circadian rhythms controlling sleep were out of sync in a quarter of young people with depression in this Sydney-based study. Read more
The sleep switch that builds muscle, burns fat, and boosts brainpower
UC Berkeley researchers mapped the brain circuits that control growth hormone during sleep, uncovering a feedback system where sleep fuels hormone release, and the hormone regulates wakefulness. The discovery helps explain links between poor sleep, obesity, diabetes, and cognitive decline, while opening new paths for treating sleep and metabolic disorders.
Down From the Trees, Humans Finally Got a Decent Night’s Sleep (Published 2015)
Humans sleep more deeply but for shorter periods than other primates’ habits, a study finds. The pattern may have helped humans evolve more powerful brains.
