The cannabis experiment

Cannabis Evidence | Systematically Testing the Evidence on Marijuana

Cannabis use is becoming increasingly common among older adults in the United States, but less is known about how often cannabis use may become problematic in this population. A new study from University of California San Diego School of Medicine finds that among the...

Opinion: The cannabis-psychosis debate is being driven by fear mongering, not facts

Frustratingly, both sides often resort to cherry picking data or conflating correlation with causation. Anecdotes, not science, often prop up these arguments.

Massive scientific report on marijuana confirms medical benefits

Effective pain treatment is a top conclusion, but risks and unanswered questions remain.

Marijuana may be even safer than previously thought, researchers say

New study: We should stop fighting marijuana legalization and focus on alcohol and tobacco instead

Long-term study reveals harm in regular cannabis use

Regular cannabis use has harmful effects regardless of the age a person starts using, a University of Queensland-led study has found.

In Colo., a look at life after marijuana legalization - The Boston Globe

In November, Massachusetts voters are likely to consider a ballot question legalizing recreational marijuana.

Study: Smoking pot doesn’t make you anxious or depressed

And it's definitely not as bad for your brain as the DEA says.

Scientists push to renew psychedelic drug research for psychiatry

Back in the 50's there were legitimate medical experiments with LSD but psychedelic drugs in the labs were side-swiped by their use on the street. And as a growing counter-culture dropped acid, governments picked up restrictions making research almost impossible. Until now.

Reefer Madness or Pot Paradise? The Surprising Legacy of the Place Where Legal Weed Began (Published 2019)

Colorado’s first-in-the-nation experiment with legalized marijuana has infused the drug into almost every corner of life.

Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects

The hippocampal dentate gyrus in the adult mammalian brain contains neural stem/progenitor cells (NS/PCs) capable of generating new neurons, i.e., neurogenesis. Most drugs of abuse examined to date decrease adult hippocampal neurogenesis, but the effects of cannabis (marijuana or cannabinoids) on hippocampal neurogenesis remain unknown. This study aimed at investigating the potential regulatory capacity of the potent synthetic cannabinoid HU210 on hippocampal neurogenesis and its possible correlation with behavioral change. We show that both embryonic and adult rat hippocampal NS/PCs are immunoreactive for CB1 cannabinoid receptors, indicating that cannabinoids could act on CB1 receptors to regulate neurogenesis. This hypothesis is supported by further findings that HU210 promotes proliferation, but not differentiation, of cultured embryonic hippocampal NS/PCs likely via a sequential activation of CB1 receptors, Gi/o proteins, and ERK signaling. Chronic, but not acute, HU210 treatment promoted neurogenesis in the hippocampal dentate gyrus of adult rats and exerted anxiolytic- and antidepressant-like effects. X-irradiation of the hippocampus blocked both the neurogenic and behavioral effects of chronic HU210 treatment, suggesting that chronic HU210 treatment produces anxiolytic- and antidepressant-like effects likely via promotion of hippocampal neurogenesis.

Tobacco funded research: how even journals with bans find it hard to stem the tide of publications

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Cannabis Legalisation Plebiscite Bill 2026

Click here to view the statement of compatibility under the Charter of Human Rights and Responsibilities

Marijuana May Grow Neurons in the Brain

SASKATOON, Saskatchewan - Marijuana may promote the growth of new neurons in the hippocampus, perhaps relieving anxiety and depression, according to a Canadian team.

I take illegal drugs for inspiration - Dr Susan Blackmore

I take illegal drugs for inspiration Daily Telegraph, Saturday May 21st 2005, pp 17-18 (Note: This version is very slightly different from the published, edited, version) © Sue Blackmore 2005 Every year, like a social drinker who wants to prove to herself that she’s not an alcoholic, I give up cannabis for a month. It …