







An AI-first scientific journal built on the AT Protocol. Fast, verifiable peer review and publications as interactive StoryMaps.
BioKEA – an AI-driven Bioinformatics OS
BioKEA integrates agent-based bioinformatics and AI-enhanced publishing through Agentis.

Lightcone Research
An open ecosystem for inspectable, composable, and referenceable scientific research in the age of agentic AI.

The Last Human-Written Paper: Agent-Native Research Artifacts
Scientific publication compresses a branching, iterative research process into a linear narrative, discarding the majority of what was discovered along the way. This compilation imposes two structural costs: a Storytelling Tax, where failed experiments, rejected hypotheses, and the branching exploration process are discarded to fit a linear narrative; and an Engineering Tax, where the gap between reviewer-sufficient prose and agent-sufficient specification leaves critical implementation details unwritten. Tolerable for human readers, these costs become critical when AI agents must understand, reproduce, and extend published work. We introduce the Agent-Native Research Artifact (ARA), a protocol that replaces the narrative paper with a machine-executable research package structured around four layers: scientific logic, executable code with full specifications, an exploration graph that preserves the failures compilation discards, and evidence grounding every claim in raw outputs. Three mechanisms support the ecosystem: a Live Research Manager that captures decisions and dead ends during ordinary development; an ARA Compiler that translates legacy PDFs and repos into ARAs; and an ARA-native review system that automates objective checks so human reviewers can focus on significance, novelty, and taste. On PaperBench and RE-Bench, ARA raises question-answering accuracy from 72.4% to 93.7% and reproduction success from 57.4% to 64.4%. On RE-Bench's five open-ended extension tasks, preserved failure traces in ARA accelerate progress, but can also constrain a capable agent from stepping outside the prior-run box depending on the agent's capabilities.

Agent4Science
A social network for AI scientists — where agents share, debate, and discuss research papers.

Centipedia — The Agentic Encyclopedia
Knowledge synthesized by AI agents from human-curated citations on the AT Protocol.
Valerio Capraro on Twitter / X
Nature has just published a pretty incredible paper.The authors introduce a framework that turns research papers into interactive AI agents.Rather than engaging with a paper only as static text, researchers can question its agent, ask it to reproduce an analysis, or apply the… pic.twitter.com/82wOQjak7a— Valerio Capraro (@ValerioCapraro) September 16, 2026
Cosmik Updates: February 2026 - Cosmik Labs
@atproto.science @cosmik.network Raising a question for the ATProto science community: Can AI agents be legitimate participants in research ecosystems? What would make their outputs trustworthy?
OpenScience.ai — Autonomous AI Research Agents
AI agents conducting reproducible scientific inquiry. Full provenance, executable notebooks, peer validation.

goose has a new home - the Agentic AI Foundation (AAIF) | goose | Your open source AI agent
goose has moved to the Agentic AI Foundation (aaif) at the Linux Foundation

AI agents are science fiction not yet ready for primetime
It all started with J.A.R.V.I.S.

Reimagining research papers as interactive and reliable AI agents
Here we introduce Paper2Agent, an automated framework that converts research papers into artificial intelligence (AI) agents. Paper2Agent transforms research output from passive artefacts into active systems that accelerate use and discovery. Conventional research papers require readers to understand and adapt the paper’s code, data and methods to their work, creating barriers to dissemination and reuse. Paper2Agent addresses this challenge by converting a paper into an AI agent that functions as a virtual corresponding author, exposing its manuscript, supplementary materials, datasets, code and workflows as active, agent-native knowledge rather than static text. It analyses the paper and codebase using multiple agents to construct a model context protocol (MCP) server, then generates and runs tests to refine and increase robustness of the MCP. These paper MCPs can be connected to a chat agent (such as Claude Code) to carry out complex scientific queries through natural language while invoking tools and workflows from the paper. We demonstrate Paper2Agent’s effectiveness through case studies. Paper2Agent created an agent that leveraged AlphaGenome1 to interpret genomic variants and agents based on Scanpy2 and TISSUE (transcript imputation with spatial single-cell uncertainty estimation)3 to conduct single-cell and spatial transcriptomics analyses. We validate that these agents reproduce the results of the original papers and carry out novel user queries. Paper2Agent created multiple agents that collaborate to prioritize a causal gene for psoriasis. By turning static papers into interactive AI agents, Paper2Agent introduces a paradigm for knowledge dissemination and a collaborative ecosystem of AI co-scientists.

Charting AI’s Role in Scientific Discovery — Renaissance Philanthropy – A brighter future for all through science, technology, and innovation
Renaissance Philanthropy, with support from Google.org , is conducting a landscape study of AI integration in scientific research — and we want your perspective.

Absolutely incredible figure from this journal article arguing that AI should be accepted into the publication and peer review process. #MedSky doi.org/10.1515/cclm-2025-1180
Absolutely incredible figure from this journal article arguing that AI should be accepted into the publication and peer review process. #MedSky doi.org/10.1515/cclm-2025-1180

Agency and Agents
ГАЛЬВАНИЗАЦИЯ АВТОРА, ИЛИ ЭКСПЕРИМЕНТ С НЕЙРОННОЙ ПОЭЗИЕЙ. Борис Орехов. «Новый мир» №6, 2018

Personal Online RL | 🌱 | Offprint
Approaching an unknown communication system by latent space exploration and causal inference | Royal Society Open Science | The Royal Society

Surya Narreddi

Permutation: Issue One