







Researchers published in NEJM about using OpenAI’s o3 DeepResearch to discover strong leads in 18 previously unsolved rare diseases o3 produced *explanations* of old lab results (not diagnoses), which researchers vetted and took to the lab AI is not just a black box openai.com/index/diagnose-rare-childhood…
Using AI to help physicians diagnose rare genetic diseases affecting children
openai.comJun 19, 2026 at 5:54 PM
Using AI to help physicians diagnose rare genetic diseases affecting children
Researchers used an OpenAI reasoning model to help diagnose rare diseases, identifying 18 new diagnoses in previously unsolved cases.

swyx on Twitter / X
icymi, openai also open sourced how their deep research prompt rewriter works + the full prompts todayyou can now build your own deep research agent - with full o3/o4-mini deep research quality - in 20LOCif you're a fan of Claude Research they ALSO dropped how to add… pic.twitter.com/5moxXjzqTj— swyx (@swyx) June 27, 2025
OpenAI launches new AI model for life sciences research
Researchers are drowning in data. AI could help.

Olmo 3: Charting a path through the model flow to lead open-source AI | Ai2
Our new flagship Olmo 3 model family empowers the open source community with not only state-of-the-art open models, but the entire model flow and full traceability back to training data.
Jan-Nano : 1st Deep Research LLM
OpenAI launches new initiative to help find and patch open source bugs | TechCrunch
OpenAI is using AI to help the open source community better protect itself.

AI linked to explosion of low-quality biomedical research papers
Analysis flags hundreds of studies that seem to follow a template, reporting correlations between complex health conditions and single variables based on publicly available data sets.

Going beyond open data – increasing transparency and trust in language models with OLMoTrace | Ai2
Ai2, a non-profit research institute founded by Paul Allen, is committed to breakthrough AI to solve the world’s biggest problems.
OpenAI can’t tell if something was written by AI after all
OpenAI’s tool struggled with accuracy.

Attorney General Marshall Launches Investigation Into OpenAI and Sam Altman for Massive Artificial Intelligence Data Breach - Alabama Attorney General's Office
For Immediate Release:August 24, 2026
OpenAI launches AI model GPT-Rosalind for life sciences research
OpenAI on Thursday introduced an artificial intelligence model touting increased biology knowledge and scientific research capabilities, as the startup deepens its push into the life sciences field.

DR Tulu: An open, end-to-end training recipe for long-form deep research | Ai2
We introduce Deep Research Tulu (DR Tulu), an open post-training recipe and framework for long-form deep research agents.

OpenAI to release open-source model as AI economics force strategic shift
OpenAI plans to release its first open-weight AI model since 2019 as economic pressures mount from competitors like DeepSeek and Meta, marking a significant strategic reversal for the company behind ChatGPT.

Measuring AI’s capability to accelerate biological research in the wet lab
OpenAI introduces a real-world evaluation framework to measure how AI can accelerate biological research in the wet lab. Using GPT-5 to optimize a molecular cloning protocol, the work explores both the promise and risks of AI-assisted experimentation.

The full stack behind abundant intelligence
OpenAI CFO Sarah Friar explains how advances across chips, compute, models, and products compound to deliver more useful intelligence at greater scale and lower cost.

OpenEvolve underperforms simple autmated discovery harnesses the rest are insignificant from each other. The best choice changed across model–problem pairs. We ran a controlled study (3m+ rollouts) using repeated budget-matched runs, strong baselines, and statistical hypothesis testing.