







This is a great read and very relevant to anyone measuring outcomes at base-line and following exposure. Really lucid treatment of the pitfalls of change-scores and some easy-enough recommendations.
Peter Tennant
Oct 15, 2025 at 7:29 AM
Dispatch
An occasional update on the lab’s latest findings, appearances, and happenings.

Emerging questions in exposure, regulation, and remediation of PFAS
My research is highly interdisciplinary and includes exposure and risk analysis. Many of our colleagues have diverse backgrounds and work together to address the interdisciplinary challenges associated with PFAS contamination …I think one of the largest gaps right now is understanding the importance of different exposure pathways for the general population.Given the tremendous physical and mental toll affected communities have experienced due to their exposure to PFAS, there is an unusually strong connection between citizens and scientists, and I hope that bond will strengthen over time.

Ten Lessons From Ten Safe Withdrawal Rate Case Studies - Early Retirement Now
Last week, we published the Tenth Safe Withdrawal Rate Study! Amazing how time flies! I did about one case study every three weeks for the last 6 months! And I could even include another one if I were to count the one I did for the ChooseFI podcast back in 2017. In fact, the ChooseFI … Continue reading Ten Lessons From Ten Safe Withdrawal Rate Case Studies


New Treatment Guideline, Same Old Denialism
The science is clear. CBT and GET are not useful treatments for ME/CFS. But cognitive dissonance is a powerful force, and we can fully expect continued denials from the conspiratorial fringe


Fact Sheet 2: Post-exertional malaise (PEM)
Fact Sheet 2: Post-exertional malaise (PEM) Published May 2025 Link to pdf: PEM_Factsheet.pdf Link to pdf of French translation: Malaise_post_effort-S4ME-Feuille_information.pdf Discussion...
‘You don’t want to get better’: the outdated treatment of ME/CFS patients is a national scandal | George Monbiot
The notion that this illness is psychosomatic is having devastating effects, says Guardian columnist George Monbiot

88 Prompts for Long Term Thinking
In January 2019 I wrote out scores of prompts for thinking long term that I felt should inform the foundation I was later co-chair of, The Long Now Foundation.

Dream of the Red Chamber
This textbook is currently being revised, so content may change between visits.

A Heterogeneous Slopes Approach to Difference-in-Differences with Non-Binary Treatments
I extend the approach of Wooldridge (2023, 2025) to allow for heterogeneous gains to treatment in the context of staggered interventions for non-binary treatmen
Fact Sheet 3: ME/CFS: Information for Medical Professionals
Fact Sheet 3: ME/CFS: Information for Medical Professionals Published December 2025 Link to pdf: ME/CFS: Information for Medical Professionals.pdf Discussion thread: Fact sheet #3: Information...
Related work | Data Counterfactuals
Adjacent research areas and starting papers, curated in Semble and synced into the site.

Has anyone looked at this paper more closely? I've seen many of my bachelor students refer to it when it comes to depressive disorders. Authors find worldwide depression rates doubled from 1990 to 2020, which seems like a lot. pubmed.ncbi.nlm.nih.gov/40313474/
Trends in Prevalent Cases and Disability-Adjusted Life-Years of Depressive Disorders Worldwide: Findings From the Global Burden of Disease Study From 1990 to 2021 - PubMed
pubmed.ncbi.nlm.nih.govGood news, everyone! I have a short piece coming out in The Conversation on Monday that explains the main issues with this study. It's impossible for me to have the same media reach as the original press release. So I'd be extremely grateful if people could help me share it as widely as possible 🙏
G. Willow Wilson
Good news, everyone cnn.com/2026/05/14/health/arts-ageing…
What is the impact of IMF structural adjustment on social outcomes in the global South? Our analysis in the BMJ Global Health compiles evidence from existing empirical studies with advanced methods. The record is devastating. Buckle up:🧵 gh.bmj.com/content/bmjgh/11/Suppl_1/e017…