A new vision of the brain as a fully integrated, networked organ.Popular neuroscience accounts often focus on specific mind-brain aspects like addiction, c
Inventing the future: A neuroscience research roadmap
The past decade of transformative advances in neurotechnology portends an exciting future for neuroscience. This NeuroView charts a strategic path to accelerate and integrate research discovery and speed the development of new cures for human brain disorders.
Open-source software reveals complete 3D architecture of brain cells
The neurons in our brain that underlie thought connect to each other using tiny branch-like structures on their surfaces known as dendritic spines. Now scientists at Columbia's Zuckerman Institute and ...
Brainchildren
Minds are complex artifacts, partly biological and partly social; only a unified, multidisciplinary approach will yield a realistic theory of how they came i...
Joshua Park on Twitter / X
It’s hard to categorize or evaluate second-brain systems because there’s no single right answer.But I found one useful lens every second brain should be evaluated through: the lifecycle of your data.Collect -> Organize -> Evolve -> Use -> GovernSo I made a curated… pic.twitter.com/GrmBFLwvEW— Joshua Park (@JoshuaIPark) May 31, 2026
BrainMind
At this important juncture in neuroscience, the BrainMind ecosystem is combining the most talented of these groups in novel ways to collectively shepherd, support, and fund ideas that can be translated from labs into interventions that will benefit humanity.
Introducing The Psyche Network
The brain in the machine: How AI could help explain how we think | IBM
Scientists are using large AI models to predict patterns of brain activity at scale, a development that researchers say is pushing neuroscience toward a new kind of digital imaging.
The inner screen model of consciousness: applying the free energy principle directly to the study of conscious experience
This paper presents a model of consciousness that follows directly from the free- energy principle (FEP). We first rehearse the classical and quantum formulations of the FEP. In particular, we consider the “inner screen hypothesis” that follows from the quantum information theoretic version of the FEP. We then review applications of the FEP to the known sparse (nested and hierarchical) neuro-anatomy of the brain. We focus on the holographic structure of the brain, and how this structure supports (overt and covert) action.
560 – Ecological Cognition II: Resonance
560 What the heck does the brain do in Ecological Dynamics, if it isn’t computing, processing, or representing? An introduction to the concept of Resonance.Download link
To Make Sense of the Present, Brains May Predict the Future | Quanta Magazine
A controversial theory suggests that perception, motor control, memory and other brain functions all depend on comparisons between ongoing actual experiences and the brain’s modeled expectations.
Embracing the suboptimal organization of the human brain
Human brain architecture is guiding brain-inspired artificial intelligence (AI) and has been treated as an optimal template, whose deviations could mark different psychiatric and neurological conditions. We argue this premise is wrong: under any single goal (e.g., minimal wiring cost or maximal communication efficiency), the human connectome is suboptimal. Instead, its organization reflects multi-objective trade-offs navigated over evolution and development under biological and environmental constraints. For psychopathology, atypical trajectories are not distances from an ideal brain but reweighted compromises in the same trade-off space. For neuro-AI, directly duplicating the brain’s connectivity risks copying its irrelevant compromises. Treating brains and models as products of multi-objective optimization and co-tuning relevant objectives offers a more powerful framework for interpreting clinical phenotypes and designing next-generation AI.
Smoke-away on Twitter / X
Andrej Karpathy: "What you want is the inner thought monologue of your brain... The trajectories in your brain as you're doing problem solving, if we had a billion of that, AGI is here roughly speaking." pic.twitter.com/C0kBUITPBv— Smoke-away (@SmokeAwayyy) October 18, 2024
Computational Psychiatry Needs Systems Neuroscience
This piece was originally published in The Transmitter. I am adapting it here with some additional context for readers of this newsletter.
Leading Innovation in Psychiatric Treatment | Alto Neuroscience
We leverage brain biology to develop personalized medicines, helping patients get better faster.
How to think like a Hegelian | Psyche Guides
For Hegel, your thoughts aren’t trapped in a cerebral box: they act on the world, making meaning and expressing your freedom
