







A Second Brain template implemented in 11ty supporting wikilinks, Obsidian, and more
Obsidian AI Second Brain: The Free Self-Organizing Plugin | Agrici Daniel
claude-obsidian turns Obsidian into a self-organizing AI second brain. 15 skills, v1.9 Compound Vault, plain Markdown you own. MIT licensed, zero manual filing.

Build an AI Second Brain(LLM Wiki Pattern) With Claude Code and Obsidian
TLDR:Build an AI-powered knowledge base in Obsidian. Use Claude Code slash commands to ingest, link, and query your notes into a smart…

I Gave Pi Access to Obsidian And I'm Not Looking Back
The REAL Second Brain: an autonomous, self-hosted knowledge wiki that runs on cheap local models
How I turned Karpathy's "LLM wiki" sketch into a system that actually maintains itself — no frontier API, no human in the loop, nothing leaving my LAN.

claude-obsidian
Self-organizing AI second brain for Obsidian + Claude Code. Drop any source and Claude reads, links, and files it into one connected knowledge graph of plain Markdown you own. AI note-taking, personal knowledge management (PKM), and an open-source Notion alternative. Based on Karpathy's LLM Wiki pattern.
Tolaria
A second brain for the AI era. Free forever, local-first, Markdown-based, Git-ready, and AI-friendly.
Automate AI Second Brain(LLM Wiki Pattern) With Claude Code and Obsidian
TLDR:Build an AI second brain with Claude Code & Obsidian. Automate daily briefings, backups & calendar sync.

nubrain - A foundation model for neural decoding
Building the world's largest dataset of human brain activity.

Joshua Park on Twitter / X
It’s hard to categorize or evaluate second-brain systems because there’s no single right answer.But I found one useful lens every second brain should be evaluated through: the lifecycle of your data.Collect -> Organize -> Evolve -> Use -> GovernSo I made a curated… pic.twitter.com/GrmBFLwvEW— Joshua Park (@JoshuaIPark) May 31, 2026

Nenex: A Neural Personal Wiki Idea
Proposal for a personal wiki built on neural nets: all edits are logged & used to finetune a NN assistant in realtime.

E11 Bio | Moonshot Neuroscience
An FRO building scalable single-cell brain circuit mapping.

Open-source software reveals complete 3D architecture of brain cells
The neurons in our brain that underlie thought connect to each other using tiny branch-like structures on their surfaces known as dendritic spines. Now scientists at Columbia's Zuckerman Institute and ...

Stanford scientists discover the human brain may actually be two separate organs
Scientists have found that the human brain develops from two distinct cellular systems, suggesting that evolution fused together two ancient nervous systems with very different jobs. The discovery also allowed researchers to grow human hindbrain neurons in the lab, opening new possibilities for studying ALS, spinal muscular atrophy, and other brainstem diseases.

How To Build LLM Wiki In Obsidian? 🧠 A Memory Layer For Any Agentic AI

I Built a Digital Brain Upload Using Karpathy's LLM Knowledge Base