







Authors: Silvia Sellán, Columbia University and Oded Stein, University of Southern California
Early science acceleration experiments with GPT-5
AI models like GPT-5 are an increasingly valuable tool for scientists, but many remain unaware of the capabilities of frontier AI. We present a collection of short case studies in which GPT-5 produced new, concrete steps in ongoing research across mathematics, physics, astronomy, computer science, biology, and materials science. In these examples, the authors highlight how AI accelerated their work, and where it fell short; where expert time was saved, and where human input was still key. We document the interactions of the human authors with GPT-5, as guiding examples of fruitful collaboration with AI. Of note, this paper includes four new results in mathematics (carefully verified by the human authors), underscoring how GPT-5 can help human mathematicians settle previously unsolved problems. These contributions are modest in scope but profound in implication, given the rate at which frontier AI is progressing.

Kevin Weil 🇺🇸 on Twitter / X
💥 Today we’re introducing Prism—a free, AI-native workspace for scientists to write and collaborate on research, powered by GPT-5.2.Accelerating science requires progress on two fronts:1. Frontier AI models that use scientific tools and can tackle the hardest problems2.… pic.twitter.com/cnLysHixuQ— Kevin Weil 🇺🇸 (@kevinweil) January 27, 2026
Modern GPU Programming For MLSys — Modern GPU Programming For MLSys
Machine learning systems sit at the heart of modern AI workloads. In these systems, performance often comes down to the quality of a small number of GPU kernels. Attention kernels, LLM prefill and decode kernels, low-precision block-scaled GEMMs, fused MoE layers, and other large fused kernels all directly shape end-to-end speed in both training and serving.
Modern GPU Programming For MLSys — Modern GPU Programming For MLSys
Machine learning systems sit at the heart of modern AI workloads. In these systems, performance often comes down to the quality of a small number of GPU kernels. Attention kernels, LLM prefill and decode kernels, low-precision block-scaled GEMMs, fused MoE layers, and other large fused kernels all directly shape end-to-end speed in both training and serving.
karpathy/minGPT
A minimal PyTorch re-implementation of the OpenAI GPT (Generative Pretrained Transformer) training
Introducing GPT-Rosalind for life sciences research
OpenAI introduces GPT-Rosalind, a frontier reasoning model built to accelerate drug discovery, genomics analysis, protein reasoning, and scientific research workflows.

pytudes/ipynb/Economics.ipynb at main · norvig/pytudes
Python programs, usually short, of considerable difficulty, to perfect particular skills. - norvig/pytudes
Flower: Advance Collaborative Superintelligence
Flower is a full-stack AI neolab with a mission to advance collaborative superintelligence by building open-source frontier models, agents, and infrastructure.

Accelerating life sciences research
Discover how a specialized AI model, GPT-4b micro, helped OpenAI and Retro Bio engineer more effective proteins for stem cell therapy and longevity research.

Brilliant | Your Personal Tutor for Math and Coding
Visual, interactive tutoring in math and coding, from 5th grade through college. Master concepts in algebra, calculus, Python, computer science, and more.

#neuroscience #ai #python #opensource #neuroai | Jean-Rémi King | 34 comments
⚡ We're happy to release NeuralSet: a fast, simple, and scalable Python framework for Neuro-AI. Already supports: 🧠 fMRI, EEG, MEG, iEEG, spikes… recordings 💬 text, 🔊 audio, ▶️ video, 🏞️ image… embeddings 📦 `pip install neuralset` 💻 Code: https://lnkd.in/eamwxBUY 📄 Paper: https://lnkd.in/epbreyDy Made possible thanks to: Hubert Banville, Katie Begany, Corentin Bel, Yohann Benchetrit, Teon Brooks, Marlène Careil, Simon Dahan, Stéphane d'Ascoli, Alexandre Défossez, Linnea Evanson, PhD, Pablo J. Diego Simón, Julien Gadonneix, Sophia Houhamdi, Shubh Khanna, Jarod Lévy, Pierre Orhan, Antoine Ratouchniak, Joséphine Raugel, Andrea Elena Santos Revilla, Alexis Thual, Lucy (Mingfang) Zhang, Jérémy RAPIN #Neuroscience #AI #Python #OpenSource #NeuroAI | 34 comments on LinkedIn
#neuroscience #ai #python #opensource #neuroai | Jean-Rémi King | 34 comments
⚡ We're happy to release NeuralSet: a fast, simple, and scalable Python framework for Neuro-AI. Already supports: 🧠 fMRI, EEG, MEG, iEEG, spikes… recordings 💬 text, 🔊 audio, ▶️ video, 🏞️ image… embeddings 📦 `pip install neuralset` 💻 Code: https://lnkd.in/eamwxBUY 📄 Paper: https://lnkd.in/epbreyDy Made possible thanks to: Hubert Banville, Katie Begany, Corentin Bel, Yohann Benchetrit, Teon Brooks, Marlène Careil, Simon Dahan, Stéphane d'Ascoli, Alexandre Défossez, Linnea Evanson, PhD, Pablo J. Diego Simón, Julien Gadonneix, Sophia Houhamdi, Shubh Khanna, Jarod Lévy, Pierre Orhan, Antoine Ratouchniak, Joséphine Raugel, Andrea Elena Santos Revilla, Alexis Thual, Lucy (Mingfang) Zhang, Jérémy RAPIN #Neuroscience #AI #Python #OpenSource #NeuroAI | 34 comments on LinkedIn

Introducing CUDA Rust: Two Tracks for Writing GPU Kernels | NVIDIA Technical Blog
In September 2026, NVIDIA announced it is leaning into native GPU programming in Rust. CUDA C++ and CUDA Python are mature, enterprise-grade toolchains, and NVIDIA will be growing and maturing CUDA…
