Life Lessons from a Lifestyle Business

Metascience Since 2012: A Personal History

This essay is a personal history of the $60+ million I allocated to metascience starting in 2012 while working for the Arnold Foundation (now Arnold Ventures).

Matt Webb

I have worked with some of the world’s largest firms on design-led product invention using new technology for over 20 years. I was MD of two London startup accelerators with R/GA Ventures, and co-founder and CEO of pioneering design studio BERG, where we shipped connected products and got work into the New York MoMA.

Re:filtered #24: A craft that outlasts an industry

A year-end reflection on building.

The Power of Habit: Why We Do What We Do in Life and Business by Charles Duhigg

A young woman walks into a laboratory. Over the past two years, she has transformed almost every ...

The Real Story Of How I Sold Two Startups, The Chaos Afterwards, And What’s Next – The Health Care Blog

Today we’re starting a series of more personal stories, looking at what makes interesting people in health care tick. Alex Carmichael is a rare multiple time CEO in health technology, and she has a very interesting tale to tell–Matthew Holt

Cancer Capital: It sucks for founders, too! - Anil Dash

A blog about making culture. Since 1999.

Reflections on Anthropic and EA

Personal reflections I've been sitting on lately.

The Filter Bubble

Lynn Parramore interviews Internet activist Eli Pariser, board president of MoveOn.org, about the filter bubble our internet habits create:

Interviews with Failed & Successful Startup Founders

+200 interviews with the brains behind shut down and active startups. Learn from their wins and their mistakes and become a better founder.

Advice for First Time Founders | Y Combinator

We operate a platform called Bookface for YC founders to connect with each other, ask questions, find intros, and share advice. Recently on Bookface Zach Dixon [https://twitter.com/zachdixongg], cofounder of the gaming company Players’ Lounge [https://playerslounge.co/] (W18), asked a great question: 1. What are some things that you should’ve known as a first-time founder but did not? 2. How did you learn them? 3. How did they help? There were so many useful answers that we’re going to share

Medium and Twitter founder: ‘We put junk food in front of them and they eat it’

Ev Williams on feedback loops, giving a home to publishers, and finding critical mass

Jason Cohen on Twitter / X

Pick advice that matches your goals.Lots of people recommend Peter Thiel's Zero to One. That’s wonderful if you're aiming to build the next Facebook.But if your focus is on creating a self-funded company prioritizing happiness and profits, that advice is incorrect.— Jason Cohen (@asmartbear) May 11, 2024

Taking on the Technosphere: A Kitchen Debate

In his original writings on the technosphere from the early 2010s, Peter Haff identified its existence as a grand metabolizing system. Back in early 2016, spurred on by the preparation for HKW’s Anthropocene Campus: The Technosphere Issue, a vehement debate sprang up in the home of science and technology scholars Gabrielle Hecht and Paul N. Edwards: How valid is Haff’s approach? What is its overall reality? And what is its heuristic purpose? In this republication of their dispute, you, the reader, can engage alongside Hecht and Edwards in the ongoing question of whether the concept of the technosphere is indeed “a useful tool,” “silverware,” or “a barren gadget” in understanding the current and future condition of planet Earth.