How can large language models (LLMs) contribute to social science research, and what parts of research remain stubbornly human? Building on existing LLM tools, we offer a multi-agent workflow capable of producing a full quantitative social science paper from an initial prompt. The workflow relies on researchers codifying their heuristics for doing data analysis, and we suggest some core design principles for researchers interested in building on this scaffolding. Using this case, we also examine what current LLM capabilities reveal about the organization of research. LLM agents can lower the cost of pursuing high-risk ideas, expand robustness and transparency, reduce concerns about the scientific file drawer, and force scholars to articulate the heuristics that create valuable work. But they also pose challenges, both in terms of the quality of papers and in the adequacy of scientific institutions to adapt. Meeting these challenges will require new institutional norms that make use of these tools observable, auditable, and accountable.
The unintended consequences of large language models as a labor-augmenting technology in science
As a labor-augmenting technology, large language models (LLMs) have the potential to accelerate scientific activity across the research pipeline. But even if LLMs perform on par with human experts at selected tasks, their use will bring unintended consequences as they alter the balance of frictions and inducements that steer the allocation of research effort across projects. Here we develop a simple mathematical model to illustrate. In fields where LLMs are useful primarily as tools for discovering promising projects, researchers will become more selective about what they publish; where they facilitate the process of publishing existing data, researchers will become less selective. By allowing scientists to work more quickly, LLMs raise the opportunity cost of researcher time, creating incentives to refine papers less thoroughly before moving on. Enticing as it is to imagine that, by saving us time on mundane tasks, LLMs will provide us with more time to think deeply and develop projects completely, our results temper such hopes.
The unintended consequences of large language models as a labor-augmenting technology in science
As a labor-augmenting technology, large language models (LLMs) have the potential to accelerate scientific activity across the research pipeline. But even if LLMs perform on par with human experts at selected tasks, their use will bring unintended consequences as they alter the balance of frictions and inducements that steer the allocation of research effort across projects. Here we develop a simple mathematical model to illustrate. In fields where LLMs are useful primarily as tools for discovering promising projects, researchers will become more selective about what they publish; where they facilitate the process of publishing existing data, researchers will become less selective. By allowing scientists to work more quickly, LLMs raise the opportunity cost of researcher time, creating incentives to refine papers less thoroughly before moving on. Enticing as it is to imagine that, by saving us time on mundane tasks, LLMs will provide us with more time to think deeply and develop projects completely, our results temper such hopes.
Scientific production in the era of Large Language Models
Large Language Models (LLMs) are rapidly reshaping scientific research. We analyze these changes in multiple, large-scale datasets with 2.1M preprints, 28K peer review reports, and 246M online accesses to scientific documents. We find: 1) scientists adopting LLMs to draft manuscripts demonstrate a large increase in paper production, ranging from 23.7-89.3% depending on scientific field and author background, 2) LLM use has reversed the relationship between writing complexity and paper quality, leading to an influx of manuscripts that are linguistically complex but substantively underwhelming, and 3) LLM adopters access and cite more diverse prior work, including books and younger, less-cited documents. These findings highlight a stunning shift in scientific production that will likely require a change in how journals, funding agencies, and tenure committees evaluate scientific works.
Topics, Authors, and Institutions in Large Language Model Research: Trends from 17K arXiv Papers
Large language models (LLMs) are dramatically influencing AI research, spurring discussions on what has changed so far and how to shape the field's future. To clarify such questions, we analyze a new dataset of 16,979 LLM-related arXiv papers, focusing on recent trends in 2023 vs. 2018-2022. First, we study disciplinary shifts: LLM research increasingly considers societal impacts, evidenced by 20x growth in LLM submissions to the Computers and Society sub-arXiv. An influx of new authors -- half of all first authors in 2023 -- are entering from non-NLP fields of CS, driving disciplinary expansion. Second, we study industry and academic publishing trends. Surprisingly, industry accounts for a smaller publication share in 2023, largely due to reduced output from Google and other Big Tech companies; universities in Asia are publishing more. Third, we study institutional collaboration: while industry-academic collaborations are common, they tend to focus on the same topics that industry focuses on rather than bridging differences. The most prolific institutions are all US- or China-based, but there is very little cross-country collaboration. We discuss implications around (1) how to support the influx of new authors, (2) how industry trends may affect academics, and (3) possible effects of (the lack of) collaboration.
Topics, Authors, and Institutions in Large Language Model Research: Trends from 17K arXiv Papers
Large language models (LLMs) are dramatically influencing AI research, spurring discussions on what has changed so far and how to shape the field's future. To clarify such questions, we analyze a new dataset of 16,979 LLM-related arXiv papers, focusing on recent trends in 2023 vs. 2018-2022. First, we study disciplinary shifts: LLM research increasingly considers societal impacts, evidenced by 20x growth in LLM submissions to the Computers and Society sub-arXiv. An influx of new authors -- half of all first authors in 2023 -- are entering from non-NLP fields of CS, driving disciplinary expansion. Second, we study industry and academic publishing trends. Surprisingly, industry accounts for a smaller publication share in 2023, largely due to reduced output from Google and other Big Tech companies; universities in Asia are publishing more. Third, we study institutional collaboration: while industry-academic collaborations are common, they tend to focus on the same topics that industry focuses on rather than bridging differences. The most prolific institutions are all US- or China-based, but there is very little cross-country collaboration. We discuss implications around (1) how to support the influx of new authors, (2) how industry trends may affect academics, and (3) possible effects of (the lack of) collaboration.
The Last Human-Written Paper: Agent-Native Research Artifacts
Scientific publication compresses a branching, iterative research process into a linear narrative, discarding the majority of what was discovered along the way. This compilation imposes two structural costs: a Storytelling Tax, where failed experiments, rejected hypotheses, and the branching exploration process are discarded to fit a linear narrative; and an Engineering Tax, where the gap between reviewer-sufficient prose and agent-sufficient specification leaves critical implementation details unwritten. Tolerable for human readers, these costs become critical when AI agents must understand, reproduce, and extend published work. We introduce the Agent-Native Research Artifact (ARA), a protocol that replaces the narrative paper with a machine-executable research package structured around four layers: scientific logic, executable code with full specifications, an exploration graph that preserves the failures compilation discards, and evidence grounding every claim in raw outputs. Three mechanisms support the ecosystem: a Live Research Manager that captures decisions and dead ends during ordinary development; an ARA Compiler that translates legacy PDFs and repos into ARAs; and an ARA-native review system that automates objective checks so human reviewers can focus on significance, novelty, and taste. On PaperBench and RE-Bench, ARA raises question-answering accuracy from 72.4% to 93.7% and reproduction success from 57.4% to 64.4%. On RE-Bench's five open-ended extension tasks, preserved failure traces in ARA accelerate progress, but can also constrain a capable agent from stepping outside the prior-run box depending on the agent's capabilities.
AI Research Agents Narrow Scientific Exploration
AI research agents can now generate research ideas, design experiments, run code, and draft papers, raising the possibility of large-scale AI-assisted scientific discovery. Many current agent frameworks explicitly encourage the generation of novel and high-impact ideas. Yet it remains unclear whether AI-assisted ideation broadens scientific exploration or mainly concentrates around existing work. We study AI research agents as scientific search systems. Using four AI research-agent frameworks and six large language models, we generate 37,802 scientific ideas from shared seed literature across citation-defined research areas in AI and machine learning. We then compare the resulting AI ideas against human-authored papers from the same research areas, follow-on human research emerging from the same seed literature, and the seed literature itself. Across experiments, four consistent patterns emerge. First, AI-generated ideas are substantially more concentrated than human-authored papers from the same research areas. Second, AI-generated ideas remain much closer to their starting literature than later human follow-on work does. Third, papers most similar to AI-generated ideas tend to receive lower subsequent citations. Fourth, when AI-generated ideas differ from prior work, the differences arise primarily from recombining existing technical methods rather than introducing fundamentally new research questions. Overall, current AI research agents appear better suited to local elaboration than to broadening scientific exploration.
Steps Towards an Infrastructure for Scholarly Synthesis
Sharing, reusing, and synthesizing knowledge is central to the research process, both individually, and with others. These core functions are not supported by our formal scholarly publishing infrastructure: instead of the smooth functioning of functional infrastructure, researchers resort to laborious "hacks" and workarounds to "mine" publications for what they need, and struggle to efficiently share the resulting information with others. Information scientists have proposed an alternative infrastructure based on the more appropriately granular model of a discourse graph of claims, and evidence, along with key rhetorical relationships between them. However, despite significant technical progress on standards and platforms, the predominant infrastructure remains steadfastly document-based. Drawing from infrastructure studies, we locate the current infrastructural bottlenecks in the lack of local systems that integrate discourse-centric models to augment synthesis work, from which an infrastructure for synthesis can be grown. Through 3 years of research through design and field deployment in a distributed community of hypertext notebook users, we elaborate a design vision of what can and should be built in order to grow a discourse-centric synthesis infrastructure: a thriving "installed base" of researchers authoring local, shareable discourse graphs to improve synthesis work, enhance primary research and research training, and augment collaborative research. We discuss how this design vision -- and our empirical work -- contributes steps towards a new infrastructure for synthesis, and increases HCI's capacity to advance collective intelligence and solve infrastructure-level problems.
Steps Towards an Infrastructure for Scholarly Synthesis
Sharing, reusing, and synthesizing knowledge is central to the research process, both individually, and with others. These core functions are not supported by our formal scholarly publishing infrastructure: instead of the smooth functioning of functional infrastructure, researchers resort to laborious ”hacks” and workarounds to ”mine” publications for what they need, and struggle to efficiently share the resulting information with others. Information scientists have proposed an alternative infrastructure based on the more appropriately granular model of a discourse graph of claims, and evidence, along with key rhetorical relationships between them. However, despite significant technical progress on standards and platforms, the predominant infrastructure remains steadfastly document-based. Drawing from infrastructure studies, we locate the current infrastructural bottlenecks in the lack of local systems that integrate discourse-centric models to augment synthesis work, from which an infrastructure for synthesis can be grown. Through 3 years of research through design and field deployment in a distributed community of hypertext notebook users, we elaborate a design vision of what can and should be built in order to grow a discourse-centric synthesis infrastructure: a thriving “installed base” of researchers authoring local, shareable discourse graphs to improve synthesis work, enhance primary research and research training, and augment collaborative research. We discuss how this design vision — and our empirical work — contributes steps towards a new infrastructure for synthesis, and increases HCI’s capacity to advance collective intelligence and solve infrastructure-level problems.
Language agents achieve superhuman synthesis of scientific knowledge
Language models are known to hallucinate incorrect information, and it is unclear if they are sufficiently accurate and reliable for use in scientific research. We developed a rigorous human-AI comparison methodology to evaluate language model agents on real-world literature search tasks covering information retrieval, summarization, and contradiction detection tasks. We show that PaperQA2, a frontier language model agent optimized for improved factuality, matches or exceeds subject matter expert performance on three realistic literature research tasks without any restrictions on humans (i.e., full access to internet, search tools, and time). PaperQA2 writes cited, Wikipedia-style summaries of scientific topics that are significantly more accurate than existing, human-written Wikipedia articles. We also introduce a hard benchmark for scientific literature research called LitQA2 that guided design of PaperQA2, leading to it exceeding human performance. Finally, we apply PaperQA2 to identify contradictions within the scientific literature, an important scientific task that is challenging for humans. PaperQA2 identifies 2.34 +/- 1.99 contradictions per paper in a random subset of biology papers, of which 70% are validated by human experts. These results demonstrate that language model agents are now capable of exceeding domain experts across meaningful tasks on scientific literature.
The Discovery Engine: A Framework for AI-Driven Synthesis and Navigation of Scientific Knowledge Landscapes
Scientific progress relies on the effective accumulation, synthesis, and critical evaluation of knowledge. Traditionally, the well-documented, peer reviewed publication served as the primary standard for filtering and disseminating credible findings within the scientific community. Recently, however, we are witnessing an unprecedented acceleration in research output, a veritable explosion of scientific publications across all disciplines [1]. Yet, this very abundance creates a paradox: the sheer volume threatens to overwhelm the mechanisms designed for its assimilation and synthesis. Researchers, even within highly specialized subfields, face an almost insurmountable challenge in keeping abreast of relevant developments, integrating disparate findings, and identifying the truly novel signals amidst the noise [2]. This information overload contributes to disciplinary fragmentation, hindering the cross-pollination of ideas essential for disruptive innovation [3]. Furthermore, persistent concerns regarding "reproducibility crisis" [2], predatory journals, inflation of research areas[4], growing retractions and the potential influences of bibliometrics on research direction [5] highlight systemic challenges in validating and prioritizing scientific contributions to fundamental knowledge.
A Novel Kuhnian Ontology for Epistemic Classification of STM Scholarly Articles
Despite rapid gains in scale, research evaluation still relies on opaque, lagging proxies. To serve the scientific community, we pursue transparency: reproducible, auditable epistemic classification useful for funding and policy. Here we formalize KGX3 as a scenario-based model for mapping Kuhnian stages from research papers, prove determinism of the classification pipeline, and define the epistemic manifold that yields paradigm maps. We report validation across recent corpora, operational complexity at global scale, and governance that preserves interpretability while protecting core IP. The system delivers early, actionable signals of drift, crisis, and shift unavailable to citation metrics or citations-anchored NLP. KGX3 is the latest iteration of a deterministic epistemic engine developed since 2019—originating as Soph.io (2019–2020), advanced as iKuhn (2020–2024), and field-tested through Preprint Watch.
Governing the scholarly AI Commons – Open Future
New report explores how academic communities can shape AI governance in research and publishing, from regulation to community-led approaches.
Metagov x Future of Science Seminar - Discourse Graphs with Matt Akamatsu
Towards Automating Scientific Review with Google's Paper Assistant Tool
Artificial intelligence is driving a revolution in scientific discovery, accelerating everything from hypothesis generation to mathematical theorem proving. However, this rapid acceleration is creating a systemic challenge: traditional human peer review cannot scale to match the influx of AI-assisted science. Ultimately, to resolve this tension, we must also deploy AI to accelerate the verification and review process itself. To frame the discussion around this transition, we propose a taxonomy consisting of four progressive levels of AI-human collaboration in scientific evaluation, and discuss various trade-offs involved with each. As a step toward this future, we introduce the Paper Assistant Tool (PAT), an agentic AI framework built for deep scientific review and verification. PAT ingests full scientific manuscripts and produces a comprehensive evaluation, checking theoretical results, validating experiments, suggesting improvements, and identifying potential flaws. By utilizing inference scaling techniques, PAT is able to identify deeper issues than a single model call alone, achieving a 34% improvement over zero-shot recall on mathematical errors in the SPOT benchmark. Pilot deployments of PAT as a pre-submission tool for authors at two major Computer Science conferences -- STOC and ICML -- demonstrate its ability to identify critical errors and suggest substantive improvements to research papers. By catching errors early, PAT eases the cognitive burden placed on referees, while preserving their control over the outcomes of the review process.
Can AI Agents Synthesize Scientific Conclusions?
Scientific AI agents increasingly retrieve evidence, reason across sources, and synthesize conclusions used in consequential decisions. Yet, their ability to do so in high-stakes domains such as health remains unclear. We introduce SciConBench, a large-scale live benchmark of 9.11K questions and expert-written conclusions from systematic reviews to evaluate open-domain scientific conclusion synthesis. The benchmark draws on an expert-validated automated evaluation pipeline that decomposes conclusions into atomic facts and measures correctness and comprehensiveness via factual precision and recall. To mitigate data leakage, we further introduce SciConHarness, a clean-room evaluation harness that equips agents with controlled web interaction to ensure valid measurement. Evaluating 8 frontier models and deep research agents, we find that factual quality remains low: under clean-room settings, the best agent achieves only a factual F1 of 0.337. Our clean-room setting consistently reduces performance relative to unconstrained evaluation, suggesting that leakage inflates estimates of models' true synthesis capabilities. Finally, we audit consumer-facing agents (e.g., Google AI Overview, OpenEvidence) and find they frequently generate incomplete and sometimes contradictory conclusions, even when the ground-truth answer is available. Overall, our results show that reliable synthesis of scientific conclusions remains an open challenge, and that clean-room evaluation is essential for assessing open-domain AI agents.