Egon Willighagen (@egonw@social.edu.nl)

(PDF) Highly efficient genome editing using oocyte-specific z cas9 transgenic zebrafish

PDF | Since its first application, CRISPR/Cas9 rapidly becomes a routine technique to perform genome editing in a variety of biological systems. To... | Find, read and cite all the research you need on ResearchGate

Jason Shepherd on Twitter / X

I have quite a lot of thoughts on this..that won't fit in a tweet. Bottomline is that there are issues scientists in the US would love to improve - faster review, less grant writing, more stability and freedom to do risky science. The folks celebrating this doc are mostly../1 https://t.co/xlPAH9XYNC— Jason Shepherd (@JasonSynaptic) July 23, 2026

AI-designed nucleases build on nature’s design

Researchers used AI to create variants of a CRISPR-Cas12-like nuclease, some of which show increased editing activity

Introducing Hypothesis commenting on bioRxiv and medRxiv: an updated way to engage with preprints - openRxiv

An important part of our mission at openRxiv is to collaborate with other organizations to improve science communication and promote interoperability. Preprints are just one part of the research workflow, and we want to ensure they are effectively integrated with the tools and communities that drive scientific progress. Today, we’re excited to share about another…

Correction of scientific literature: Too little, too late!

The Coronavirus Disease 2019 (COVID-19) pandemic has highlighted the limitations of the current scientific publication system, in which serious post-publication concerns are often addressed too slowly to be effective. In this Perspective, we offer suggestions to improve academia’s willingness and ability to correct errors in an appropriate time frame.

Making sense of preprints by adding context – The Publish Your Reviews initiative - LSE Impact

Improving scientific publishing is often framed as an issue of openness and speed and less often as one of context. In this post, Ludo Waltman and Jessica Polka make the case for a more contextualised approach to open access publishing and preprinting, and introduce the Publish Your Reviews initiative. Launched today by ASAPbio, the initiative

Why we built the Journal of Research on Research and what it cost us - LSE Impact

Gemma Derrick, Bart Penders, Serge Horbach & Tony Ross-Hellauer reflect on the choices, challenges & compromises of launching the Journal of Research on Research

NLnet; Nanoarguments

Scientific knowledge is currently scattered across papers, repositories, and disconnected platforms, with no structured way to trace how claims connect to evidence or how arguments develop. Nanoarguments builds a framework and tools for creating, browsing, and contributing to a global, federated graph of scientific discourse and evidence. Researchers and their communities can collaboratively structure claims, evidence chains, and discussion as nanopublications, which are small, cryptographically signed Linked Data snippets with precise provenance and authorship, published to a decentralized peer-to-peer network. The project builds upon the Nanodash interface to help users browse, edit, and aggregate discourse and evidence graphs, and integrates with dokieli to enable in-context authoring of nanopublications as inline annotations while reading or writing a document. A bidirectional ActivityPub connector bridges the nanopublication network and the fediverse, allowing discourse threads to start as social exchanges and crystallize into persistent, machine-readable evidence records. The project will be piloted with early adopter research groups in discourse and evidence modeling. All components will be released as open-source modules that other systems can build upon.

What happened to Science Goodreads and how do we rebuild it? A 65 million dollar question (at least) - Cosmik Labs

The story of the rise and fall of Mendeley