Hot Allostatic Load

Post-exertional malaise (PEM) in ME/CFS

Post-exertional malaise (PEM), the cardinal feature of ME/CFS, is particularly debilitating as it involves the amplification of existing symptoms, alongside the potential appearance of new ones, following minimal exertion. However, the term “exertion” may be misconstrued, by those unfamiliar with ME/CFS, as activities typically considered high intensity by healthy individuals. Consequently, healthy individuals may inappropriately…

Home | Reasons To Stay

When the world feels heavy, a kind word can make a difference. Receive anonymous letters from people who have been there. No pressure, no spam—just a quiet reminder that you are not alone.

Introducing Noema VI: Paradigm Shifts | NOEMA

Profound transformations occurring simultaneously mark our new Age of Upheaval.

Trauma Junkie

[First place winner in the Synapse Storytelling Contest for Fiction.] It’s Christmastime, and over the hills, in the faraway furrows of one of those endless tracts of half-submerged land, a main battle tank sits in a ditch, decomposing, festering. My tank. But the neighborhood seems to have forgotten, here in the shadow of the old Hospital, that shining ziggurat high above. An aspiration, once — and an obligation.

Burnout Phase Transition - meri's missives

Modelling chronic stress effects on my mental health and the end of monopolies

Dopamine Trap

Dopamine Trap does narrative driven decay. With organic noise, apocalyptic soundscapes, and scathing poetry his productions cast lovecraftian solopsisms on the roof of the skull, dripping with tumors of unresolved inter-generational trauma, resignation and reckless, violent love. He delights in emptiness and the granular implications of percussive silence.

Fact Sheet 2: Post-exertional malaise (PEM)

Fact Sheet 2: Post-exertional malaise (PEM) Published May 2025 Link to pdf: PEM_Factsheet.pdf Link to pdf of French translation: Malaise_post_effort-S4ME-Feuille_information.pdf Discussion...

Positech@CSCW2026

People care about climate change, injustice, and humanitarian crises. The challenge is not apathy but capacity: sustained engagement with large-scale problems is psychologically costly, and social media architecture often amplifies awareness while providing few pathways to meaningful action.

Open Source Burnout Claims Another Project

Yet another OSS maintainer quits because of burnout. To fix this, we need better mental health resources for maintainers.

The modern struggle Lone individuals summoning inhuman willpower, fasting, meditating, and exercising, up against armies of scientists & statisticians weaponizing abundant food, screens, & medicine into junk food, clickbait news, infinite porn, endless games & addictive drugs.

The modern struggleLone individuals summoning inhuman willpower,fasting, meditating, and exercising,up against armies of scientists & statisticians weaponizing abundant food, screens, & medicine into junk food, clickbait news, infinite porn, endless games & addictive drugs.— Naval (@naval) January 14, 2019

Low on energy? A new understanding of rest could help revitalise you

There is a state of relaxation that few of us spend much time in, but which comes with profound well-being benefits. With healthier ageing, reduced risk of disease and feeling more energised all on offer, here's how to get there

Amy Deng on Twitter / X

I’m an AI researcher turned brain tumor patient, and recently I used the models to crack my mystery fatigue faster than my PCP could. I believe everyone can do the same with their own symptoms. Here’s how: pic.twitter.com/0jhbPvEi7V— Amy Deng (@amydeng_) June 16, 2026