The volume of scientific manuscripts is rising faster than the available pool of expert reviewers, and AI tools are emerging as a possible response, ranging from frontier large language models applied directly to peer review to purpose-built multi-agent systems. Scalable, standardized benchmarks are needed to regularly evaluate how these tools compare to one another and to human reviewers. We present ReviewBench, an open-source, venue-agnostic framework that compares human and AI reviews across structure, alignment with a paper’s major claims, impact, and critique category. We apply ReviewBench to 145,021 review comments from human reviewers, frontier large language models (GPT-5.2, and Gemini 3 Pro), and Reviewer3.com (R3), a multi-agent peer review system. The dataset spans papers in computer science (ICLR 2025, n = 1,000), social science (Nature Human Behaviour, n = 142), and life science (eLife, n = 1,000). Across disciplines, AI reviews are more structured and engage more directly with a paper’s major claims, with R3 more often surfacing consequential comments, defined as comments capable of undermining those claims. When restricting to critical comments, however, human reviewers rank first on consequential rate on more individual papers than any AI source, despite a lower average. We identify a bimodal reviewer distribution with peaks near 0% and 100%, indicating that many reviewers outperform AI on this metric, but a substantial fraction of reviewers near 0% brings the average down. Critique typing demonstrates systematic differences, where humans emphasize contribution and clarity, while AI emphasizes validity, sufficiency, and transparency. Together, these findings argue against framing AI as a replacement for human review and instead support a complementary model in which AI scales technical verification of major claims while human judgment remains essential for evaluating contribution and shaping editorial decisions.
AI-Assisted Peer Review at Scale: The AAAI-26 AI Review Pilot
Scientific peer review faces mounting strain as submission volumes surge, making it increasingly difficult to sustain review quality, consistency, and timeliness. Recent advances in AI have led the community to consider its use in peer review, yet a key unresolved question is whether AI can generate technically sound reviews at real-world conference scale. Here we report the first large-scale field deployment of AI-assisted peer review: every main-track submission at AAAI-26 received one clearly identified AI review from a state-of-the-art system. The system combined frontier models, tool use, and safeguards in a multi-stage process to generate reviews for all 22,977 full-review papers in less than a day. A large-scale survey of AAAI-26 authors and program committee members showed that participants not only found AI reviews useful, but actually preferred them to human reviews on key dimensions such as technical accuracy and research suggestions. We also introduce a novel benchmark and find that our system substantially outperforms a simple LLM-generated review baseline at detecting a variety of scientific weaknesses. Together, these results show that state-of-the-art AI methods can already make meaningful contributions to scientific peer review at conference scale, opening a path toward the next generation of synergistic human-AI teaming for evaluating research.
Position: The ML Community Must Build an AI-Augmented Peer-Review Ecosystem
Peer review, the bedrock of scientific advancement in machine learning (ML), is strained by a crisis of scale. Exponential growth in manuscript submissions to premier ML venues such as NeurIPS, ICML, and ICLR is outpacing the finite capacity of qualified reviewers, leading to concerns about review quality, consistency, and reviewer fatigue. This position paper argues that AI-assisted peer review must become an urgent research and infrastructure priority. We advocate for a comprehensive AI-augmented ecosystem, leveraging Large Language Models (LLMs) not as replacements for human judgment, but as sophisticated collaborators for authors, reviewers, and Area Chairs (ACs). We propose specific roles for AI in enhancing factual verification, guiding reviewer performance, assisting authors in quality improvement, and supporting ACs in decision-making. Crucially, we contend that the development of such systems hinges on access to more granular, structured, and ethically-sourced peer review process data. We outline a research agenda, including illustrative experiments, to develop and validate these AI assistants, and discuss significant technical and ethical challenges. We call upon the ML community to proactively build this AI-assisted future, ensuring the continued integrity and scalability of scientific validation, while maintaining high standards of peer review.
Towards Automating Scientific Review with Google's Paper Assistant Tool
Artificial intelligence is driving a revolution in scientific discovery, accelerating everything from hypothesis generation to mathematical theorem proving. However, this rapid acceleration is creating a systemic challenge: traditional human peer review cannot scale to match the influx of AI-assisted science. Ultimately, to resolve this tension, we must also deploy AI to accelerate the verification and review process itself. To frame the discussion around this transition, we propose a taxonomy consisting of four progressive levels of AI-human collaboration in scientific evaluation, and discuss various trade-offs involved with each. As a step toward this future, we introduce the Paper Assistant Tool (PAT), an agentic AI framework built for deep scientific review and verification. PAT ingests full scientific manuscripts and produces a comprehensive evaluation, checking theoretical results, validating experiments, suggesting improvements, and identifying potential flaws. By utilizing inference scaling techniques, PAT is able to identify deeper issues than a single model call alone, achieving a 34% improvement over zero-shot recall on mathematical errors in the SPOT benchmark. Pilot deployments of PAT as a pre-submission tool for authors at two major Computer Science conferences -- STOC and ICML -- demonstrate its ability to identify critical errors and suggest substantive improvements to research papers. By catching errors early, PAT eases the cognitive burden placed on referees, while preserving their control over the outcomes of the review process.
PaperOrchestra: A Multi-Agent Framework for Automated AI Research Paper Writing
Synthesizing unstructured research materials into manuscripts is an essential yet under-explored challenge in AI-driven scientific discovery. Existing autonomous writers are rigidly coupled to specific experimental pipelines, and produce superficial literature reviews. We introduce PaperOrchestra, a multi-agent framework for automated AI research paper writing. It flexibly transforms unconstrained pre-writing materials into submission-ready LaTeX manuscripts, including comprehensive literature synthesis and generated visuals, such as plots and conceptual diagrams. To evaluate performance, we present PaperWritingBench, the first standardized benchmark of reverse-engineered raw materials from 200 top-tier AI conference papers, alongside a comprehensive suite of automated evaluators. In side-by-side human evaluations, PaperOrchestra significantly outperforms autonomous baselines, achieving an absolute win rate margin of 50%-68% in literature review quality, and 14%-38% in overall manuscript quality.
Policies Permitting LLM Use for Polishing Peer Reviews Are Currently Not Enforceable
A number of scientific conferences and journals have recently enacted policies that prohibit LLM usage by peer reviewers, except for polishing, paraphrasing, and grammar correction of otherwise human-written reviews. But, are these policies enforceable? To answer this question, we assemble a dataset of peer reviews simulating multiple levels of human-AI collaboration, and evaluate five state-of-the-art detectors, including two commercial systems. Our analysis shows that all detectors misclassify a non-trivial fraction of LLM-polished reviews as AI-generated, thereby risking false accusations of academic misconduct. We further investigate whether peer-review-specific signals, including access to the paper manuscript and the constrained domain of scientific writing, can be leveraged to improve detection. While incorporating such signals yields measurable gains in some settings, we identify limitations in each approach and find that none meets the accuracy standards required for identifying AI use in peer reviews. Importantly, our results suggest that recent public estimates of AI use in peer reviews through the use of AI-text detectors should be interpreted with caution, as current detectors misclassify mixed reviews (collaborative human-AI outputs) as fully AI generated, potentially overstating the extent of policy violations.
Can AI Agents Synthesize Scientific Conclusions?
Scientific AI agents increasingly retrieve evidence, reason across sources, and synthesize conclusions used in consequential decisions. Yet, their ability to do so in high-stakes domains such as health remains unclear. We introduce SciConBench, a large-scale live benchmark of 9.11K questions and expert-written conclusions from systematic reviews to evaluate open-domain scientific conclusion synthesis. The benchmark draws on an expert-validated automated evaluation pipeline that decomposes conclusions into atomic facts and measures correctness and comprehensiveness via factual precision and recall. To mitigate data leakage, we further introduce SciConHarness, a clean-room evaluation harness that equips agents with controlled web interaction to ensure valid measurement. Evaluating 8 frontier models and deep research agents, we find that factual quality remains low: under clean-room settings, the best agent achieves only a factual F1 of 0.337. Our clean-room setting consistently reduces performance relative to unconstrained evaluation, suggesting that leakage inflates estimates of models' true synthesis capabilities. Finally, we audit consumer-facing agents (e.g., Google AI Overview, OpenEvidence) and find they frequently generate incomplete and sometimes contradictory conclusions, even when the ground-truth answer is available. Overall, our results show that reliable synthesis of scientific conclusions remains an open challenge, and that clean-room evaluation is essential for assessing open-domain AI agents.
AI’s Growing Role as Scientific Peer Reviewer | Stanford HAI
Stanford computer scientist James Zou is exploring how AI can accelerate scientific research and peer review. His finding: AI excels at spotting gaps, but judgment calls still need humans.
How do authors want to use AI for review?
A survey of researchers who compared AI-generated scientific reviews with journal-agnostic human peer review reveals that they overwhelmingly prefer using AI as a self-checking tool before submission rather than as a replacement for human reviewers. It encourages an “author-centric” model in which AI helps researchers improve their manuscripts before they are reviewed by their peers.
ScientistTwo: Pioneering the Human Knowledge Frontier with Autonomous AI
Scientific discovery is defined by the ability to identify the boundaries of existing knowledge and venture into unexplored territory. The ultimate vision for AI in science is problem-driven autonomous research: given a fundamental challenge by a human expert, the AI independently navigates the scientific landscape, uncovers theoretical and empirical bottlenecks, and systematically expands the frontier of knowledge. In this paper, we introduce ScientistTwo, a fully autonomous multi-agent framework designed to realize this vision. Specifically, ScientistTwo takes an initial problem as input, establishes state-of-the-art baselines, formulates novel hypotheses, and coordinates specialized agents to orchestrate an end-to-end discovery cycle without human intervention. Moreover, the framework rigorously conducts experiments using diverse datasets and metrics, refines methodologies through automated ablation studies, and validates research findings via a closed-loop simulated peer-review rebuttal engine. To evaluate ScientistTwo's capabilities against the highest standards of human scientific achievement, we benchmark it across papers accepted at top-tier conferences such as ICLR, ICML, and NeurIPS. As a result, ScientistTwo autonomously generates expert-level, publishable papers and fully verified, executable codebases. Its solutions consistently outperform human state-of-the-art models, and achieve higher average review ratings than human-authored papers under automated AI review agents. These results show that ScientistTwo is not merely an assistive tool but an autonomous scientific pioneer capable of pushing the frontiers of human discovery. Project website: https://scientist-two.github.io/
Language agents achieve superhuman synthesis of scientific knowledge
Language models are known to hallucinate incorrect information, and it is unclear if they are sufficiently accurate and reliable for use in scientific research. We developed a rigorous human-AI comparison methodology to evaluate language model agents on real-world literature search tasks covering information retrieval, summarization, and contradiction detection tasks. We show that PaperQA2, a frontier language model agent optimized for improved factuality, matches or exceeds subject matter expert performance on three realistic literature research tasks without any restrictions on humans (i.e., full access to internet, search tools, and time). PaperQA2 writes cited, Wikipedia-style summaries of scientific topics that are significantly more accurate than existing, human-written Wikipedia articles. We also introduce a hard benchmark for scientific literature research called LitQA2 that guided design of PaperQA2, leading to it exceeding human performance. Finally, we apply PaperQA2 to identify contradictions within the scientific literature, an important scientific task that is challenging for humans. PaperQA2 identifies 2.34 +/- 1.99 contradictions per paper in a random subset of biology papers, of which 70% are validated by human experts. These results demonstrate that language model agents are now capable of exceeding domain experts across meaningful tasks on scientific literature.
InsightEval: An Expert-Curated Benchmark for Assessing Insight Discovery in LLM-Driven Data Agents
Data analysis has become an indispensable part of scientific research. To discover the latent knowledge and insights hidden within massive datasets, we need to perform deep exploratory analysis to realize their full value. With the advent of large language models (LLMs) and multi-agent systems, more and more researchers are making use of these technologies for insight discovery. However, there are few benchmarks for evaluating insight discovery capabilities. As one of the most comprehensive existing frameworks, InsightBench also suffers from many critical flaws: format inconsistencies, poorly conceived objectives, and redundant insights. These issues may significantly affect the quality of data and the evaluation of agents. To address these issues, we thoroughly investigate shortcomings in InsightBench and propose essential criteria for a high-quality insight benchmark. Regarding this, we develop a data-curation pipeline to construct a new dataset named InsightEval. We further introduce a novel metric to measure the exploratory performance of agents. Through extensive experiments on InsightEval, we highlight prevailing challenges in automated insight discovery and raise some key findings to guide future research in this promising direction.
The Last Human-Written Paper: Agent-Native Research Artifacts
Scientific publication compresses a branching, iterative research process into a linear narrative, discarding the majority of what was discovered along the way. This compilation imposes two structural costs: a Storytelling Tax, where failed experiments, rejected hypotheses, and the branching exploration process are discarded to fit a linear narrative; and an Engineering Tax, where the gap between reviewer-sufficient prose and agent-sufficient specification leaves critical implementation details unwritten. Tolerable for human readers, these costs become critical when AI agents must understand, reproduce, and extend published work. We introduce the Agent-Native Research Artifact (ARA), a protocol that replaces the narrative paper with a machine-executable research package structured around four layers: scientific logic, executable code with full specifications, an exploration graph that preserves the failures compilation discards, and evidence grounding every claim in raw outputs. Three mechanisms support the ecosystem: a Live Research Manager that captures decisions and dead ends during ordinary development; an ARA Compiler that translates legacy PDFs and repos into ARAs; and an ARA-native review system that automates objective checks so human reviewers can focus on significance, novelty, and taste. On PaperBench and RE-Bench, ARA raises question-answering accuracy from 72.4% to 93.7% and reproduction success from 57.4% to 64.4%. On RE-Bench's five open-ended extension tasks, preserved failure traces in ARA accelerate progress, but can also constrain a capable agent from stepping outside the prior-run box depending on the agent's capabilities. Our code is open-sourced at https://github.com/Orchestra-Research/Agent-Native-Research-Artifact.
HalluCiteChecker: A Lightweight Toolkit for Hallucinated Citation Detection and Verification in the Era of AI Scientists
We introduce HalluCiteChecker, a toolkit for detecting and verifying hallucinated citations in scientific papers. While AI assistant technologies have transformed the academic writing process, including citation recommendation, they have also led to the emergence of hallucinated citations that do not correspond to any existing work. Such citations not only undermine the credibility of scientific papers but also impose an additional burden on reviewers and authors, who must manually verify their validity during the review process. In this study, we formalize hallucinated citation detection as an NLP task and provide a corresponding toolkit as a practical foundation for addressing this problem. Our package is lightweight and can perform verification in seconds on a standard laptop. It can also be executed entirely offline and runs efficiently using only CPUs. We hope that HalluCiteChecker will help reduce reviewer workload and support organizers by enabling systematic pre-review and publication checks. Our code is released under the Apache 2.0 license on GitHub and is distributed as an installable package via PyPI. A demonstration video is available on YouTube.
Major AI conference flooded with peer reviews written fully by AI
Nature - Controversy has erupted after 21% of manuscript reviews for an international AI conference were found to be generated by artificial intelligence.
Towards End-to-End Automation of AI Research
The automation of science is a long-standing ambition in the field of AI. While the community has made significant progress in automating individual components of the scientific process, a system that autonomously navigates the entire research lifecycle -- from conception to publication -- has remained out of reach. Here, we present the strongest demonstration to date toward automating the entire process end-to-end. We present The AI Scientist, which creates research ideas, writes code, runs experiments, plots and analyzes data, writes the entire scientific manuscript and performs its own peer review. Its ideas, execution, and presentation are of sufficient quality to produce a manuscript generated by an AI system that passes the first round of peer review at a major machine learning conference workshop. The workshop has an acceptance rate of 70 percent. Our system leverages modern foundation models within a complex agentic system. We evaluate The AI Scientist in two settings: a focused mode using human-provided code templates as an initial scaffold to conduct research on a specific topic, and a template-free, open-ended mode that leverages agentic search for wider scientific exploration. Both settings produce diverse ideas and automatically test, report on, and evaluate them. This achievement demonstrates AI's growing capacity for scientific contribution and signifies a potential paradigm shift in how research is conducted. As with any impactful new technology, there could be significant risks, including taxing overwhelmed review systems and adding noise to scientific literature. However, if developed responsibly, such autonomous systems could greatly accelerate scientific discovery.