







Accidental drug overdoses can be life threatening but for two women who took massive hits of LSD the experience was life changing – in a good way.
How LSD Microdosing Became the Hot New Business Trip
Regular doses of acid have become the creativity enhancer of choice for some professionals

Intravenous Methylphenidate Abuse
Data are presented from a case series of 22 patients who abused methylphenidate hydrochloride (Ritalin-SR). The abuse pattern and symptoms of toxicity were similar to that seen with cocaine hydrochloride and amphetamine sulfate addiction; yet, the morbidity and mortality seen in this case series...

Flashback! Psychedelic research returns
Four decades after Timothy Leary, LSD shows success in medical trials. Will the right completely trip?

LSD: The Geek's Wonder Drug | Hacker News
One sketch pad had a long black squiggle on it, the same design you'd make if you fell asleep while holding a pen to paper, and the rest had even less (One was literally two 1" lines forming a 90 degree angle). The next day they described the night as a huge success even though they never really attained any of their stated goals.
Scientists push to renew psychedelic drug research for psychiatry
Back in the 50's there were legitimate medical experiments with LSD but psychedelic drugs in the labs were side-swiped by their use on the street. And as a growing counter-culture dropped acid, governments picked up restrictions making research almost impossible. Until now.

Brain scans reveal how LSD affects consciousness
Drug researcher David Nutt discusses brain-imaging studies with hallucinogens.

Severe toxicity due to injected but not oral or nasal abuse of methylphenidate tablets
BACKGROUND:Non-medical use of methylphenidate is increasing. Little is known about potential acute medical complications associated with recreational use of methylphenidate. STUDY AIM: To identify medical problems associated with methylphenidate abuse. METHODS: Retrospective case series of methylphenidate abuse cases presenting to an inner city emergency department. RESULTS: We identified 14 cases of methylphenidate abuse between 2003 and 2010. Ten of these patients abused methylphenidate alone while four co-ingested other drugs, mainly alcohol. The route of ingestion was oral in nine patients, nasal in one and intravascular in four. Severe toxicity was exclusively observed in users who injected the drug. Two cases involved accidental intra-arterial injection and resulted in tissue necrosis leading to the amputation of a forearm and of fingertips, respectively. Clinical findings in the non-serious cases included mild to moderate symptoms and signs of sympathetic nervous stimulation such as agitation, tachycardia, hypertension, anxiety, hallucination, headache, tremor and dizziness. Nine of the fourteen patients were taking methylphenidate as a prescribed drug. Eight patients were former or current multiple substance abusers. CONCLUSION: Methylphenidate misuse is not a significant burden for emergency departments in Switzerland. Oral and nasal administration of methylphenidate did not result in severe toxicity. However, injection of crushed methylphenidate pills lead to serious local toxicity. Most patients with methylphenidate abuse had a prescription for the drug indicating deviation from medical use. A history of multiple substance use may be a risk factor for non-medical use of methylphenidate.
The Early, State-Sanctioned LSD Experiments in Communist Bulgaria
Bulgarians were turning on, tuning in, and dropping out long before hippies.

Acid test: how psychedelic virtual reality can help end society's mass bad trip
Cyberdelic VR is being used to treat trauma and even simulate near-death experiences

I take illegal drugs for inspiration - Dr Susan Blackmore
I take illegal drugs for inspiration Daily Telegraph, Saturday May 21st 2005, pp 17-18 (Note: This version is very slightly different from the published, edited, version) © Sue Blackmore 2005 Every year, like a social drinker who wants to prove to herself that she’s not an alcoholic, I give up cannabis for a month. It …

Sanitizing the Psychedelic Revolution
Big Pharma is rushing to monetize ancient healing practices, but what’s left might not be the same medicine

The medications that change who we are
They’ve been linked to road rage, pathological gambling, and complicated acts of fraud. It turns out many ordinary medications don’t just affect our bodies – they affect our brains.

How easy is it to get addicted to methylphenidate?
Hi so I (18m) will start taking prescripted methylphenidate (medikinet) next thursday and i’ve never taken any stimulants (besides caffeine and…
Opinion | The Failed War on Drugs (Published 2018)
Attacking rampant drug abuse by trying to shut off the supply has not worked. We need to try a new approach.

Brain scans show how LSD mimics mind of a baby
Scientists have for the first time scanned the brains of people using LSD and found the psychedelic drug frees the brain to become less compartmentalized and more like the mind of a baby.
From treating PTSD to quitting tobacco: researchers say public investment into psychedelic drugs essential | CBC News
Magic mushrooms to treat depression, ecstasy to cure PTSD and LSD to combat alcoholism; just some of the drug-affliction pairings that have been tested in recent years.
