







In Reinventing Discovery, Michael Nielsen argues that w…
The Engine of Scientific Discovery: How New Methods and Tools Spark Major Breakthroughs
Abstract. How do we spark new scientific discoveries? Why do some breakthroughs seem even accidental? And most importantly, how can we accelerate them and

Michael Nielsen – How science actually progresses
Infinite Researchers | AI-Powered Scientific Discovery
What happens to the speed of discovery if we have infinite researchers? Explore AI experiments accelerating breakthroughs.

Governing by dismantling: tech oligarchy and the stifling of public data infrastructure
Published in Science as Culture (Ahead of Print, 2026)

How AI Agents are transforming scientific discovery
AI agents are starting to reshape science, from proposing novel hypotheses to writing code. Learn what comes next for scientists and policymakers.
Inventing New Nature
Defining the Protocol Institute's research mission

AI as the Catalyst of the New Paradigm of Science? | Cadmus Journal
The rapid advancement of Artificial Intelligence (AI) is reshaping the landscape of scientific inquiry. This article examines the challenges confronting modern science, including knowledge fragmentation, diminishing returns of current paradigms, and the disconnect between science and society. It explores how AI offers solutions enhancing collaboration and integrating knowledge—as well as considers the possible “darker side” of using AI in research. However, the advent of AI in science not only enhances scientific research but also redefines the role of human researchers and fosters a new paradigm of human understanding. By embracing these transformations, a more cohesive and responsive scientific enterprise can emerge.
Science Live: Platform for FAIR Nanopublications
Science Live Platform - Transform research into connected knowledge
Coordination Tech in Science: Letters, Journals, and Whatever Comes Next | shishyko!
To modernize our scientific infrastructure, we need new contextualization and coordination technologies that decouple trust from legacy branding — shifting from gatekeeping on write to algorithmic contextualization on read.
Rebuilding the Architecture of Science
Science built the modern world. It’s time to rebuild the world of science.

Science has been in a “replication crisis” for a decade. Have we learned anything?
Bad papers are still published. But some other things might be getting better.

Sensemaking Networks: Project Introduction - Cosmik Labs
Incorporating science social media into the scientific process
Index Network: Discovery Protocol
Finding people living in New York who listen to avant-garde jazz and curious about the semantic web, or discovering the latest events attended by peo...

Open Science Network
Reclaim scientific discourse with federated digital spaces where researchers shape their own conversations, data, and collaborations

Remarkable how over a decade ago @michaelnielsen.bsky.social pointed the way towards solving long standing issues plaguing science to this day (issues that are all the more relevant in the age of AI mediated science)
Ronen Tamari
This is why @atproto.science is so relevant rn This compilation of essays indicates that scientists are most frustrated by insufficient “community tools and resources... Essential infrastructure for sharing, maintaining and building on existing work and data is also badly underdeveloped." >