Dysthymia

Depression doesn't shrink the brain like we thought it did | New Scientist

For the past decade, depression has been linked to a shrunken hippocampus, which has a vital role in memory. But a large study using up-to-date scanning techniques suggests this may not be the case

Autistic Burnout vs. Depression | Neurodivergent Insights

Dr Megan Anna Neff explains the difference between autistic burnout and depression. Overlapping signs, root causes, and why withdrawal can be a valid response.

(PDF) Neuroendocrine, Autonomic and Metabolic Challenges in Hypermobile Ehlers-Danlos Syndrome- A Case Study on Hypoglycemia in a patient with Craniocervical Instability.. Medical Research Archives. [Online] 12-5

PDF | This report presents a compelling case of hypoglycemia in a 20-year-old female with craniocervical instability receiving chronic total parenteral... | Find, read and cite all the research you need on ResearchGate

Hypoglycemia Associated With Hypermobile Ehlers-Danlos Syndrome

Abstract. Hypoglycemia in the absence of diabetes is often multifactorial and challenging to diagnose definitively. We present a case report and an expande

Degeneracy is a Symptom

On Conspicuous Despair, the Ponzi stage of being alive, and why your grandparents are wrong about you.

Navigating the Odyssey of Refractory Hypoglycemia: A Diagnostic and Therapeutic Puzzle in Ehlers-Danlos Syndrome Managed With Octreotide

Author Block: Mehwish Zeb, Michigan State University, Yarub Al-Alousi, St. Joseph University Medical Center, Syed Farasat Ali Shah, Institute of Diabetes and Endocrinology

Progesterone – Friend or foe?

Estradiol is the “prototypic” sex hormone of women. Yet, women have another sex hormone, which is often disregarded: Progesterone. The goal of this article is to provide a comprehensive review on progesterone, and its metabolite allopregnanolone, emphasizing three key areas: biological properties, main functions, and effects on mood in women. Recent years of intensive research on progesterone and allopregnanolone have paved the way for new treatment of postpartum depression. However, treatment for premenstrual syndrome and premenstrual dysphoric disorder as well as contraception that women can use without risking mental health problems are still needed. As far as progesterone is concerned, we might be dealing with a two-edged sword: while its metabolite allopregnanolone has been proven useful for treatment of PPD, it may trigger negative symptoms in women with PMS and PMDD. Overall, our current knowledge on the beneficial and harmful effects of progesterone is limited and further research is imperative.

Premenstrual Dysphoric Disorder Symptoms Following Ovarian Suppression: Triggered by Change in Ovarian Steroid Levels But Not Continuous Stable Levels | American Journal of Psychiatry

Objective:Premenstrual dysphoric disorder (PMDD) symptoms are eliminated by ovarian suppression and stimulated by administration of ovarian steroids, yet they appear with ovarian steroid levels indistinguishable from those in women without PMDD. Thus, ...

Eiko Fried (@eikofried.bsky.social)

Professor of Mental Health & Data Science at Leiden University. Studying mental health problems as systems (http://eiko-fried.com). Building an early warning system for depression (http://WARN-D.com).

Can One Donation a Day Keep Depression Away? Three Randomized Controlled Trials of an Online Micro-Charitable Giving Intervention

Prosocial interventions grounded in social interactions have shown limited effectiveness in alleviating depressive symptoms, possibly because of the discomfort and unease that depressed individuals experience during such interactions. We developed and examined an innovative prosocial intervention—an online micro-charitable giving intervention, in which individuals voluntarily donated at least one Chinese cent (¥0.01, or about $0.0014) daily. We conducted three preregistered, 2-month randomized controlled trials with depressed individuals (Sample 1: N = 125, Sample 2: N = 296, Sample 3: N = 462). Results showed that, compared with the waitlist group, the intervention group exhibited significantly greater improvements in both depressive symptoms (Cohen’s d s = −0.19 to −0.46) and emotional positivity (Cohen’s d s = 0.22 to 0.49), and that emotional positivity mediated the intervention’s effect on the reduction of depressive symptoms. Exploratory analysis found a slightly larger intervention effect for generous donors than for minimal donors. This low-cost, easily accessible prosocial intervention holds potential for the prevention of depression. Statement of Relevance Can donating one cent (specifically one Chinese cent, or about $0.0014) alleviate depressive symptoms? We have developed a practical and effective intervention—donating at least one cent daily on an online charity platform—and have discovered that this intervention effectively mitigates depressive symptoms in depressed individuals. Despite the nominal purchasing power of one cent in contemporary society, this act of giving has been shown to significantly enhance mental health. Our findings could be relevant to everyone in society; charitable donations promote societal harmony and, in addition, offer a cost-effective way to alleviate depressive symptoms. As the intervention instruction asserts, “Charity encompasses love, regardless of its size, as even one cent holds value.”

For those who’s taking ritalin / stimulants, does it drain you towards the end of the day?

80 votes, 56 comments. Im not sure if I used the right flair… Hello Reddit! I was recently diagnosed with adhd and its been a week since taking…

Dopamine Nation — Anna Lembke, MD

In Dopamine Nation, Dr. Anna Lembke, psychiatrist and author, explores the exciting new scientific discoveries that explain why the relentless pursuit of pleasure leads to pain.

Post-exertional malaise (PEM) in ME/CFS

Post-exertional malaise (PEM), the cardinal feature of ME/CFS, is particularly debilitating as it involves the amplification of existing symptoms, alongside the potential appearance of new ones, following minimal exertion. However, the term “exertion” may be misconstrued, by those unfamiliar with ME/CFS, as activities typically considered high intensity by healthy individuals. Consequently, healthy individuals may inappropriately…

Blood tests for mental health problems | Eiko Fried

A new paper was published yesterday on a blood test for schizophrenia, by the same research team that in 2021 published a paper on a blood test for depression . The papers and...