







Dysthymia is a milder, yet long-lasting form of depression.
the depression thing
the depression thing: a neat story about depression and mental health. By Zach Holman.

Depression doesn't shrink the brain like we thought it did | New Scientist
For the past decade, depression has been linked to a shrunken hippocampus, which has a vital role in memory. But a large study using up-to-date scanning techniques suggests this may not be the case

The Global Decline in the Mental Health of the Young
One of the major findings in wellbeing research until recently was that happiness was U-shaped by age and unhappiness hump-shaped by age. There was a midlife crisis — a finding reported in well over 600 published papers using data on 145 countries. It was present in both developing and developed countries. And it was persistent over time. The finding of a peak in ill-being in midlife was consistent with Anne Case and Angus Deaton’s work on mortality and the so-called “deaths of despair.”1 In the US in particular and to a lesser extent in other countries, White prime-aged individuals without a college degree had high death rates from suicide, drug overdoses, and cirrhosis of the liver. Drug overdose deaths in the US, for example, peaked at midlife ages. In 2023, the Centers for Disease Control and Prevention (CDC) reported that overdose death rates per 100,000 by age rose from 13.5 for 15-to-24-year-olds to 45.6 for 25-to-34-year-olds and 60.8 for 35-to-44-year-olds, and then declined to 53.3 for 45-to-54-year-olds, 49.2 for 55-to-64-year-olds, and 14.7 for those over the age of 65.2 The morbidity data matched the mortality data.

Autistic Burnout vs. Depression | Neurodivergent Insights
Dr Megan Anna Neff explains the difference between autistic burnout and depression. Overlapping signs, root causes, and why withdrawal can be a valid response.

(PDF) Neuroendocrine, Autonomic and Metabolic Challenges in Hypermobile Ehlers-Danlos Syndrome- A Case Study on Hypoglycemia in a patient with Craniocervical Instability.. Medical Research Archives. [Online] 12-5
PDF | This report presents a compelling case of hypoglycemia in a 20-year-old female with craniocervical instability receiving chronic total parenteral... | Find, read and cite all the research you need on ResearchGate

Hypoglycemia Associated With Hypermobile Ehlers-Danlos Syndrome
Abstract. Hypoglycemia in the absence of diabetes is often multifactorial and challenging to diagnose definitively. We present a case report and an expande

Is everything you think you know about depression wrong?
In this extract from his new book, Johann Hari, who took antidepressants for 14 years, calls for a new approach

Degeneracy is a Symptom
On Conspicuous Despair, the Ponzi stage of being alive, and why your grandparents are wrong about you.

Navigating the Odyssey of Refractory Hypoglycemia: A Diagnostic and Therapeutic Puzzle in Ehlers-Danlos Syndrome Managed With Octreotide
Author Block: Mehwish Zeb, Michigan State University, Yarub Al-Alousi, St. Joseph University Medical Center, Syed Farasat Ali Shah, Institute of Diabetes and Endocrinology
Life Is Strange Post-Game Depression Starter Kit
163 votes, 53 comments. Just finished the game and have that empty whole inside your heart? You're not alone! Lot's of people have gone through the…
Progesterone – Friend or foe?
Estradiol is the “prototypic” sex hormone of women. Yet, women have another sex hormone, which is often disregarded: Progesterone. The goal of this article is to provide a comprehensive review on progesterone, and its metabolite allopregnanolone, emphasizing three key areas: biological properties, main functions, and effects on mood in women. Recent years of intensive research on progesterone and allopregnanolone have paved the way for new treatment of postpartum depression. However, treatment for premenstrual syndrome and premenstrual dysphoric disorder as well as contraception that women can use without risking mental health problems are still needed. As far as progesterone is concerned, we might be dealing with a two-edged sword: while its metabolite allopregnanolone has been proven useful for treatment of PPD, it may trigger negative symptoms in women with PMS and PMDD. Overall, our current knowledge on the beneficial and harmful effects of progesterone is limited and further research is imperative.
Premenstrual Dysphoric Disorder Symptoms Following Ovarian Suppression: Triggered by Change in Ovarian Steroid Levels But Not Continuous Stable Levels | American Journal of Psychiatry
Objective:Premenstrual dysphoric disorder (PMDD) symptoms are eliminated by ovarian suppression and stimulated by administration of ovarian steroids, yet they appear with ovarian steroid levels indistinguishable from those in women without PMDD. Thus, ...

Eiko Fried (@eikofried.bsky.social)
Professor of Mental Health & Data Science at Leiden University. Studying mental health problems as systems (http://eiko-fried.com). Building an early warning system for depression (http://WARN-D.com).
Has anyone looked at this paper more closely? I've seen many of my bachelor students refer to it when it comes to depressive disorders. Authors find worldwide depression rates doubled from 1990 to 2020, which seems like a lot. pubmed.ncbi.nlm.nih.gov/40313474/
Trends in Prevalent Cases and Disability-Adjusted Life-Years of Depressive Disorders Worldwide: Findings From the Global Burden of Disease Study From 1990 to 2021 - PubMed
pubmed.ncbi.nlm.nih.gov