Opinion | The Real Causes Of Depression Have Been Discovered, And They're Not What You Think

When You Are Depressed, Make Something.

Depression doesn’t discriminate. Everyone is a potential target for it, regardless of gender, age, ethnicity, geographical location, or income. We are all subject to its grasp, and remember, it’s not the same thing as sadness.

Anxiety and Depression Are Symptoms, Not Diseases

It is crucial to first and foremost see anxiety and depression as symptoms of unmet needs for relational value, rather than diseases of the brain.

the depression thing

the depression thing: a neat story about depression and mental health. By Zach Holman.

Is everything you think you know about depression wrong?

In this extract from his new book, Johann Hari, who took antidepressants for 14 years, calls for a new approach

Depression linked to internal jet lag study finds

Circadian rhythms controlling sleep were out of sync in a quarter of young people with depression in this Sydney-based study. Read more

Depression doesn't shrink the brain like we thought it did | New Scientist

For the past decade, depression has been linked to a shrunken hippocampus, which has a vital role in memory. But a large study using up-to-date scanning techniques suggests this may not be the case

For the first time, scientists pinpoint brain cells linked to depression

Scientists identified two types of brain cells, neurons and microglia, that are altered in people with depression. Through genomic mapping of post-mortem brain tissue, they found major differences in gene activity affecting mood and inflammation. The findings reinforce that depression has a clear biological foundation and open new doors for treatment development.

Life Is Strange Post-Game Depression Starter Kit

163 votes, 53 comments. Just finished the game and have that empty whole inside your heart? You're not alone! Lot's of people have gone through the…

how to support people who have depression

Admit you don’t know what to say Express “I care” Remind them that they matters Check them regularly Ask how I can help, but be specific (“Could I do X?” rather than “How can I help you?“) Encourage them to see professional treatment To listen without interruptions Only claim understanding if you g...

How Annihilation Nails the Complex Reality of Depression

No film in recent memory captures the truth of self-destruction and depression quite like it.

Different ways to live with dark thoughts

How Zen Buddhism helps me with depression.

Depression's "Energy Crisis": Fatigue Starts at the Cellular Level - Neuroscience News

Depression-related fatigue is caused by cellular "overworking" at rest and a failure to produce energy under stress.

The neuroimaging correlates of depression established across six large-scale population datasets

Depression has been linked to reduced size of subcortical regions and abnormal functional connectivity in frontal and default mode networks. However, recent meta-analyses have failed to identify significant converging correlates of depression across the literature such that a conclusive mapping of the neuroimaging correlates of depression remains elusive. We leveraged 23,417 participants across 6 population datasets to comprehensively establish the neuroimaging correlates of depression. We found reductions in gray matter volume/cortical surface area associated with depression in the frontal cortex, anterior cingulate and insula, confirming previous studies showing the importance of prefrontal and default mode regions in depression. Our findings demonstrate multiple surprising results, including a lack of depression correlates in subcortical brain regions and significant depression correlates in somatomotor and visual regions. Overall, these results shed new light on key brain regions involved in the pathophysiology of depression, updating our understanding of the neuroimaging correlates of depression symptoms.

The neuroimaging correlates of depression established across six large-scale population datasets

Depression has been linked to reduced size of subcortical regions and abnormal functional connectivity in frontal and default mode networks. However, recent meta-analyses have failed to identify significant converging correlates of depression across the literature such that a conclusive mapping of the neuroimaging correlates of depression remains elusive. We leveraged 23,417 participants across 6 population datasets to comprehensively establish the neuroimaging correlates of depression. We found reductions in gray matter volume/cortical surface area associated with depression in the frontal cortex, anterior cingulate and insula, confirming previous studies showing the importance of prefrontal and default mode regions in depression. Our findings demonstrate multiple surprising results, including a lack of depression correlates in subcortical brain regions and significant depression correlates in somatomotor and visual regions. Overall, these results shed new light on key brain regions involved in the pathophysiology of depression, updating our understanding of the neuroimaging correlates of depression symptoms.

Dysthymia

Dysthymia is a milder, yet long-lasting form of depression.