







Scientists are using large AI models to predict patterns of brain activity at scale, a development that researchers say is pushing neuroscience toward a new kind of digital imaging.
Neural Computer: A New Machine Form Is Emerging
A research essay on Neural Computer: how it differs from agents, world models, and conventional computers; what runtime and CNC would mean; what current prototypes already show; and how software and hardware might change.
What the Studies Say About How AI Affects Your Brain: A (Very Big) Compilation
The entire literature clearly points to a single surprising finding

AI for science: What can it do? Can it do things? Let’s find out!
A what we’re reading spotlight

Mathematical methods and human thought in the age of AI
Artificial intelligence (AI) is the name popularly given to a broad spectrum of computer tools designed to perform increasingly complex cognitive tasks, including many that used to solely be the...

How AI coding is reshaping theoretical neuroscience
Agentic coding makes it possible to specify a neuroscience model in hours instead of months. Neuroscientists weigh in on that tectonic change.

The Global Brain Algorithm
<p>This is a collection of explanations on the global brain algorithm. We explain core concepts in simple terms that help to understand the algorithms as a whole.</p>

A foundation model of vision, audition, and language for in-silico neuroscience | Research - AI at Meta
Cognitive neuroscience is fragmented into specialized models, each tailored to specific experimental paradigms, hence preventing a unified model of...
NeuroAI
Neuroscience, cognitive science, and AI are all questing for principles that help generalization. Learn more through a live, synchronous program designed for focused, hands-on learning.
Deep Research, information vs. insight, and the nature of science
What AI will accelerate in the scientific process, what it cannot do, and how we can prepare for new manners of scientific investigation.

Introducing TRIBE v2: AI Model Predicts Human Brain Responses | AI at Meta posted on the topic | LinkedIn
Today we're introducing TRIBE v2, a foundation model trained to predict how the human brain responds to almost any sight or sound. Building on our Algonauts 2025 award-winning architecture, TRIBE v2 draws on 500+ hours of fMRI recordings from 700+ people to create a digital twin of neural activity. It enables zero-shot predictions for new subjects, languages, and tasks, consistently outperforming standard modeling approaches. We’re releasing the model, codebase, paper, and an interactive demo to help researchers advance neuroscience, apply brain insights to build better AI, and use computational simulation to speed up breakthroughs in neurological disease diagnosis and treatment. Try the demo and learn more here: https://go.meta.me/tribe2 | 175 comments on LinkedIn
Introducing TRIBE v2: A Predictive Foundation Model Trained to Understand How the Human Brain Processes Complex Stimuli | Keith Doelling
This is some very cool work by some awesome colleagues Jean-Rémi King, and Teon Brooks! Seriously not enough good things can be said about how cool it is. You should enjoy it and play with it. And kudos to Meta for open sourcing it. At the same time, I'm already seeing posts about how the model will replace fMRI experiments as researchers will simulate how the brain "really works" instead of running costly experiments. I think this goes WELL beyond what its creators intend. We are already seeing that use of AI in science allows you to explore charted ideas more thoroughly and much more rapidly but slows us down in finding novel ideas (https://lnkd.in/eMR2akqt). At the same time, there is growing concern that LLM performance will collapse as they are increasingly trained on their own output (https://lnkd.in/eavgfyuY). Leaving neuroscience to AI simulations risks following the same fate, where we generate seemingly new findings without gaining new meaning. A mechanistic understanding of how the brain works (if that is still your goal) will be found at the margins, in errors and idiosyncrasies of neural function. What TRIBE provides is a super useful and cool instantiation of our current understanding on how and where neural activity is instantiated in the brain. But it won't help us make groundbreaking new findings of how neural circuits lead to cognition and behavior. Experiments on real human brains, may be costly, but they will always be necessary!
Introducing TRIBE v2: A Predictive Foundation Model Trained to Understand How the Human Brain Processes Complex Stimuli | Keith Doelling
This is some very cool work by some awesome colleagues Jean-Rémi King, and Teon Brooks! Seriously not enough good things can be said about how cool it is. You should enjoy it and play with it. And kudos to Meta for open sourcing it. At the same time, I'm already seeing posts about how the model will replace fMRI experiments as researchers will simulate how the brain "really works" instead of running costly experiments. I think this goes WELL beyond what its creators intend. We are already seeing that use of AI in science allows you to explore charted ideas more thoroughly and much more rapidly but slows us down in finding novel ideas (https://lnkd.in/eMR2akqt). At the same time, there is growing concern that LLM performance will collapse as they are increasingly trained on their own output (https://lnkd.in/eavgfyuY). Leaving neuroscience to AI simulations risks following the same fate, where we generate seemingly new findings without gaining new meaning. A mechanistic understanding of how the brain works (if that is still your goal) will be found at the margins, in errors and idiosyncrasies of neural function. What TRIBE provides is a super useful and cool instantiation of our current understanding on how and where neural activity is instantiated in the brain. But it won't help us make groundbreaking new findings of how neural circuits lead to cognition and behavior. Experiments on real human brains, may be costly, but they will always be necessary!
Memorize details from AI research papers
The second brain of AI researchers for machine learning, computer vision and natural language processing paper reviews.

brainlife
The platform allows to analyze Magnetic Resonance Imaging (MRI), electroencephalography (EEG) and magnetoencephalography (MEG) data. Data can either be uploaded from local computers or imported from public archives such as OpenNeuro.org. Over 400+ data processing Apps are available on brainlife.io to build custom data workflows. Thousands of jobs can be submitted using shared clusters or on users' compute resource. Users can perform group-level statistical analysis or apply machine learning methods using Jupyter notebooks. A single record containing the entire data workflow (from raw data to published figures) can be published addressed by with a unique digital object identifier (DOI).
Introducing TRIBE v2: A Predictive Foundation Model Trained to Understand How the Human Brain Processes Complex Stimuli
Understanding how the human brain processes the world around us is one of the greatest open challenges in neuroscience. Breakthroughs here could transform how we understand and treat neurological conditions affecting hundreds of millions of people — and improve AI systems by directly guiding their development from neuroscientific principles.
