







An occasional update on the lab’s latest findings, appearances, and happenings.
PRISM: Capturing the Invisible Art of Scientific Practice
A New Tool for Recording and Scaling Laboratory Expertise

The CDC Has a Cyclospora Lab. DOGE Downsized It Last Year
“Based on simple math, these outbreak responses—which require rapid, timely responses—are going to be greatly diminished,” the former CDC lab director tells WIRED.

LabFolio
The most complete and granular data collection of scientist activities and the platform to share and collaborate with other scientists.
Alerts | Elicit: Al for scientific research
AI monitoring and screening with Elicit Alerts help you stay on top of all new research. Save a new alert mid-workflow and be notified when new relevant papers become available.

Introducing Hypothesis commenting on bioRxiv and medRxiv: an updated way to engage with preprints - openRxiv
An important part of our mission at openRxiv is to collaborate with other organizations to improve science communication and promote interoperability. Preprints are just one part of the research workflow, and we want to ensure they are effectively integrated with the tools and communities that drive scientific progress. Today, we’re excited to share about another…
Assessing and mitigating batch effects in large-scale omics studies
Batch effects in omics data are notoriously common technical variations unrelated to study objectives, and may result in misleading outcomes if uncorrected, or hinder biomedical discovery if over-corrected. Assessing and mitigating batch effects is crucial for ensuring the reliability and reproducibility of omics data and minimizing the impact of technical variations on biological interpretation. In this review, we highlight the profound negative impact of batch effects and the urgent need to address this challenging problem in large-scale omics studies. We summarize potential sources of batch effects, current progress in evaluating and correcting them, and consortium efforts aiming to tackle them.

Jason Shepherd on Twitter / X
I have quite a lot of thoughts on this..that won't fit in a tweet. Bottomline is that there are issues scientists in the US would love to improve - faster review, less grant writing, more stability and freedom to do risky science. The folks celebrating this doc are mostly../1 https://t.co/xlPAH9XYNC— Jason Shepherd (@JasonSynaptic) July 23, 2026
SenseNets alpha launch retrospective - Cosmik Labs
Experiments at the bleeding edge scientific publishing
We live in a golden age of biology. So why are people still dying from disease? Because discovery and development move slower than they should. Today, we’re partnering with Incyte to change… | Samuel G. Rodriques | 491 comments
We live in a golden age of biology. So why are people still dying from disease? Because discovery and development move slower than they should. Today, we’re partnering with Incyte to change that. Kosmos is now the first agent that can compress months of drug development into weeks, from the earliest stages of scientific discovery through to FDA approval. Incyte will be the first company to deploy it across their pipeline. Work that used to take a team of scientists months now happens in weeks. Patients can't wait, and neither can we. | 491 comments on LinkedIn
The Lab | Just Vision
The Lab provides emerging and veteran journalists with rigorous editorial guidance and mentorship, financial support for travel and reporting time, and opportunities for collaborative reporting, research and storytelling. Our journalism is produced and published in partnership with leading news organizations around the world.
Small Telescopes - Uri Simonsohn, 2015
This article introduces a new approach for evaluating replication results. It combines effect-size estimation with hypothesis testing, assessing the extent to w...

Researchers published in NEJM about using OpenAI’s o3 DeepResearch to discover strong leads in 18 previously unsolved rare diseases o3 produced *explanations* of old lab results (not diagnoses), which researchers vetted and took to the lab AI is not just a black box openai.com/index/diagnose-rare-childhood…
Using AI to help physicians diagnose rare genetic diseases affecting children
openai.com