







What AI will accelerate in the scientific process, what it cannot do, and how we can prepare for new manners of scientific investigation.
AI for science: What can it do? Can it do things? Let’s find out!
A what we’re reading spotlight

AI for science needs reasoning, not just data
AI agents that can model the human process of research will accelerate discoveries in science.

AI has supercharged scientists—but may have shrunk science
Analysis of 41 million papers finds that although AI expands individual impact, it narrows collective scientific exploration
AI co-scientists are revolutionizing how research is done
Artificial-intelligence systems can generate hypotheses, design experiments and analyse data — but humans still need to decide what makes sense.

AI scientists are changing research — institutions, funders and publishers must respond
The ability to automate the discovery process in some areas of scientific inquiry raises unanswered questions about how research should be conducted.

I don’t think we are close to “AI scientists”
Today's AI agents are not designed to extract deep insights from new observations.

AI as the Catalyst of the New Paradigm of Science? | Cadmus Journal
The rapid advancement of Artificial Intelligence (AI) is reshaping the landscape of scientific inquiry. This article examines the challenges confronting modern science, including knowledge fragmentation, diminishing returns of current paradigms, and the disconnect between science and society. It explores how AI offers solutions enhancing collaboration and integrating knowledge—as well as considers the possible “darker side” of using AI in research. However, the advent of AI in science not only enhances scientific research but also redefines the role of human researchers and fosters a new paradigm of human understanding. By embracing these transformations, a more cohesive and responsive scientific enterprise can emerge.
Where does the rigor go? Research software and the future of trustworthy science.
Generative AI now makes it dramatically easier to produce something that looks like research: analysis code, figures, literature reviews, even whole pap…

How to build an AI scientist: first peer-reviewed paper spills the secrets
AI Scientist, an autonomous research tool, first released in 2024, has now undergone peer review, highlighting its strengths and limitations.

Artificial intelligence and illusions of understanding in scientific research
Scientists are enthusiastically imagining ways in which artificial intelligence (AI) tools might improve research. Why are AI tools so attractive and what are the risks of implementing them across the research pipeline? Here we develop a taxonomy of scientists’ visions for AI, observing that their appeal comes from promises to improve productivity and objectivity by overcoming human shortcomings. But proposed AI solutions can also exploit our cognitive limitations, making us vulnerable to illusions of understanding in which we believe we understand more about the world than we actually do. Such illusions obscure the scientific community’s ability to see the formation of scientific monocultures, in which some types of methods, questions and viewpoints come to dominate alternative approaches, making science less innovative and more vulnerable to errors. The proliferation of AI tools in science risks introducing a phase of scientific enquiry in which we produce more but understand less. By analysing the appeal of these tools, we provide a framework for advancing discussions of responsible knowledge production in the age of AI.

No. 030: Google Deep Review, AI research taste, AI in dissertations - The Hallway Track
The Hallway Track No. 030 - How AI is affecting the practice of science

Science that Compounds: The Need for A New Substrate for Research in the Age of AI
This paper is a perspective from Lightcone Research, an open-source initiative building tooling for scientific research in the age of agentic AI.
Artificial intelligence tools expand scientists’ impact but contract science’s focus
Developments in artificial intelligence (AI) have accelerated scientific discovery1. Alongside recent AI-oriented Nobel prizes2–9, these trends establish the role of AI tools in science10. This advancement raises questions about the influence of AI tools on scientists and science as a whole, and highlights a potential conflict between individual and collective benefits11. To evaluate these questions, we used a pretrained language model to identify AI-augmented research, with an F1-score of 0.875 in validation against expert-labelled data. Using a dataset of 41.3 million research papers across the natural sciences and covering distinct eras of AI, here we show an accelerated adoption of AI tools among scientists and consistent professional advantages associated with AI usage, but a collective narrowing of scientific focus. Scientists who engage in AI-augmented research publish 3.02 times more papers, receive 4.84 times more citations and become research project leaders 1.37 years earlier than those who do not. By contrast, AI adoption shrinks the collective volume of scientific topics studied by 4.63% and decreases scientists’ engagement with one another by 22%. By consequence, adoption of AI in science presents what seems to be a paradox: an expansion of individual scientists’ impact but a contraction in collective science’s reach, as AI-augmented work moves collectively towards areas richest in data. With reduced follow-on engagement, AI tools seem to automate established fields rather than explore new ones, highlighting a tension between personal advancement and collective scientific progress.

Which ‘AI scientist’ suits your lab? A guide for the perplexed
General-purpose AI tools for science, such as Claude Science, promise to accelerate research. But which is right for you?

Will AI spark a scientific renaissance — or a diffuse monoculture?
Artificial intelligence’s ability to enrich science will depend not only on model capability, but also on whether researchers, reviewers and funders reward originality over speed.

Bending the Curve: How AI is Transforming Scientific Discovery
Discover how researchers use LLMs and specialized AI models like AlphaFold as complementary tools to accelerate innovation and expand the scientific frontier.