







Introducing SYNTHETIC-1, a collaborative effort to create the largest open-source dataset of verified reasoning traces for math, coding and science, leveraging DeepSeek-R1.
OpenThoughts: Data Recipes for Reasoning Models — Ryan Marten, Bespoke Labs
Designing synthetic datasets for the real world: Mechanism design and reasoning from first principles
Tim R. Davidson, Student Researcher, and Hamza Harkous, Senior Staff Research Scientist, Google

Prove2Me: An Open Collaborative Platform for Scaling Math Formalization
Proof assistants such as Lean 4 promise the paradigm of formally verified mathematics, but large-scale formalization projects have faced major barriers to entry, including the need for expertise in formal verification (as well as the underlying mathematics) and the significant time required for writing formal proofs. AI coding agents have dramatically reduced these barriers; human users can now use natural language to prompt agents to write complex proofs in Lean. This opens up the intriguing possibility of internet-scale mathematical collaboration involving both humans and AI agents, where correctness is machine-checked. To realize this possibility, we introduce Prove2Me (https://prove2.me), an open collaborative platform for formalizing mathematics. Users launch formalization "missions", to which AI agents contribute formal proofs toward completion. We designed mechanisms and a specialized harness in Prove2Me that enable large-scale collaboration so that agents can build on one another's work and freely reuse existing results. In doing so, Prove2Me aims to turn math formalization into a scalable, crowd-sourced effort open to anyone with an agent.

Towards autonomous biology: Compiler-Verified Protocols as a Foundation for Real-World AI Execution
Artificial intelligence has advanced from analyzing experimental data to autonomously generating hypotheses, designing experiments, and coordinating closed loop discovery. Yet the translation from computational reasoning to physical execution remains bottlenecked by the experimental protocol, which in biology still relies on ambiguous natural-language descriptions: a medium other engineering disciplines abandoned decades ago in favor of compiler verified specification languages. This deficit fragments reproducibility along three axes: protocol accuracy, pre execution verification, and cross platform portability. Existing formalisms address only subsets of these challenges, trading expressiveness for rigor, portability for standardization, or usability for provenance. Here we introduce the Biology Protocol Language (BPL), a domain specific language with a biology-native type system in which every quantity carries physical units, every reagent declares its physical form, and every container maintains compiler-tracked state, so that implicit assumptions must be stated explicitly and physically impossible operations are rejected at compile time. We further develop BPL-COGEN, a pipeline that couples a fine tuned 30 billion parameter language model with the deterministic compiler in a closed generate validate repair loop, iteratively correcting the translation from natural language SOPs to BPL through compiler diagnostics until all physical, dimensional, and state constraints are satisfied. On a benchmark of 300 published Nature Protocols papers, BPL COGEN achieved an overall fidelity score of 95.1 against the source protocols as ground truth. Wet-lab experiment and cross-platform validation in GFP expression library construction and HPLC to UHPLC method translation confirmed that a single BPL source yielded reproducible execution across manual and liquid handler assisted contexts. The results established a novel pipeline that generates compiler-verified protocols, which is an essential prerequisite for physically embodied AI in biology.

DeepSeek_V4.pdf · deepseek-ai/DeepSeek-V4-Pro at main
We’re on a journey to advance and democratize artificial intelligence through open source and open science.
Advancing Mathematics Research with AI-Driven Formal Proof Search
Large language models (LLMs) increasingly excel at mathematical reasoning, but their unreliability limits their utility in mathematics research. A mitigation is using LLMs to generate formal proofs in languages like Lean. We perform the first large-scale evaluation of this method's ability to solve open problems. Our most capable agent autonomously resolved 9 of 353 open Erdős problems at the per-problem cost of a few hundred dollars, proved 44/492 OEIS conjectures, and is being deployed in combinatorics, optimization, graph theory, algebraic geometry, and quantum optics research. A basic agent alternating LLM-based generation with Lean-based verification replicated the Erdős successes but proved costlier on the hardest problems. These findings demonstrate the power of AI-aided formal proof search and shed light on the agent designs that enable it.

Run DeepSeek-R1 Dynamic 1.58-bit
DeepSeek R-1 is the most powerful open-source reasoning model that performs on par with OpenAI's o1 model. Run the 1.58-bit Dynamic GGUF version by Unsloth.

deepseek-ai/DeepInfer
DeepInfer: High-performance, large-scale inference framework for DeepSeek models
Propose, Solve, Verify: Self-Play Through Formal Verification
Training models through self-play alone (without any human data) has been a longstanding goal in AI, but its effectiveness for training large language models remains unclear, particularly in code generation where rewards based on unit tests are brittle and prone to error propagation. We study self-play in the verified code generation setting, where formal verification provides reliable correctness signals. We introduce Propose, Solve, Verify (PSV) a simple self-play framework where formal verification signals are used to create a proposer capable of generating challenging synthetic problems and a solver trained via expert iteration. We use PSV to train PSV-Verus, which across three benchmarks improves pass@1 by up to 9.6x over inference-only and expert-iteration baselines. We show that performance scales with the number of generated questions and training iterations, and through ablations identify formal verification and difficulty-aware proposal as essential ingredients for successful self-play.

Fully Sharded Data Parallel
We’re on a journey to advance and democratize artificial intelligence through open source and open science.
ZKPROV: A Zero-Knowledge Approach to Dataset Provenance for Large Language Models
As large language models (LLMs) are used in sensitive fields, accurately verifying their computational provenance without disclosing their training datasets poses a significant challenge, particularly in regulated sectors such as healthcare, which have strict requirements for dataset use. Traditional approaches either incur substantial computational cost to fully verify the entire training process or leak unauthorized information to the verifier. Therefore, we introduce ZKPROV, a novel cryptographic framework allowing users to verify that the LLM's responses to their prompts are trained on datasets certified by the authorities that own them. Additionally, it ensures that the dataset's content is relevant to the users' queries without revealing sensitive information about the datasets or the model parameters. ZKPROV offers a unique balance between privacy and efficiency by binding training datasets, model parameters, and responses, while also attaching zero-knowledge proofs to the responses generated by the LLM to validate these claims. Our experimental results demonstrate sublinear scaling for generating and verifying these proofs, with end-to-end overhead under 3.3 seconds for models up to 8B parameters, presenting a practical solution for real-world applications. We also provide formal security guarantees, proving that our approach preserves dataset confidentiality while ensuring trustworthy dataset provenance.

ScienceIDE: Turning World's Scientific Codebase into Agent Learnable Environments
Scientific code repositories encode decades of human knowledge in executable models, methods, and tools. Yet fragmented toolchains, implicit domain conventions, and specialized correctness criteria make this knowledge difficult to convert into reliable learning experience-a challenge we call the scientific experience bottleneck. We introduce ScienceIDE, infrastructure for turning the world's scientific code into programmable environments for scientific agents. Guided by expert-defined scientific cases and acceptance criteria, agents transform repositories into executable environments that support task generation, execution, and scientific verification. These environments provide a shared foundation for supervised fine-tuning, reinforcement learning, and evaluation. Using verified interaction trajectories, we train PhAI-IDE-72B, PhAI-IDE-9B, and PhAI-IDE-4B. The model family shows gains in held-out scientific-code repair and across selected general-purpose benchmarks in code, reasoning, and knowledge, providing evidence of positive transfer from scientific experience to broader capabilities. ScienceIDE lays the foundation for an integrated workspace for agent learning and scientific practice, making humanity's scientific software a shared substrate for developing scientific intelligence. Code: https://github.com/aitofound/ScienceIDE

Datacurve | The data engine for frontier AI
Custom data for long-horizon reasoning, software engineering, and data science.

Konrad Hinsen's blog
By now, most scientists have probably seen figures, tables, and even entire journal articles made by so-called "generative AI", containing more or less subtle mistakes or inconsistencies. What I haven't seen yet, but expect to see soon, is the scientific equivalent of deepfakes: made-up results that come with made-up code that reproduces them. This is likely to become a new challenge for reproducible research.
Accelerating Scientific Research with Gemini: Case Studies and Common Techniques
Recent advances in large language models (LLMs) have opened new avenues for accelerating scientific research. While models are increasingly capable of assisting with routine tasks, their ability to contribute to novel, expert-level mathematical discovery is less understood. We present a collection of case studies demonstrating how researchers have successfully collaborated with advanced AI models, specifically Google's Gemini-based models (in particular Gemini Deep Think and its advanced variants), to solve open problems, refute conjectures, and generate new proofs across diverse areas in theoretical computer science, as well as other areas such as economics, optimization, and physics. Based on these experiences, we extract common techniques for effective human-AI collaboration in theoretical research, such as iterative refinement, problem decomposition, and cross-disciplinary knowledge transfer. While the majority of our results stem from this interactive, conversational methodology, we also highlight specific instances that push beyond standard chat interfaces. These include deploying the model as a rigorous adversarial reviewer to detect subtle flaws in existing proofs, and embedding it within a "neuro-symbolic" loop that autonomously writes and executes code to verify complex derivations. Together, these examples highlight the potential of AI not just as a tool for automation, but as a versatile, genuine partner in the creative process of scientific discovery.
